I am a Reader in Computational Bioinformatics and Head of the Section of Bioinformatics within the Division of Systems Medicine of the Department of Metabolism, Digestion and Reproduction. I am also Director of the MRes in Biomedical Research and Deputy Director of Post Graduate Studies for the Department. My overall research interests lie at the interface between two broad areas:

multivariate data analysis, and post-genomic technologies.

More specifically, on the computational side these include, machine learning, bioinformatics, chemometrics, and multivariate statistics, and on the experimental side, the fields of genomics, transcriptomics and metabolomics. I am interested in applying diverse computational and mathematical methods in order to disentangle the mass of information at multiple biological levels generated by the –omics technologies. The ultimate aim is to synthesise the information provided by each of these techniques, thus facilitating a multi-scale understanding of biological systems. This broad aim leads to several themes in my research:

Improving information extraction from Nuclear Magnetic Resonance (NMR) spectroscopy & Liquid Chromatography–Mass Spectrometry (LC-MS) metabolic profiles
Novel methods for predictive modelling of post-genomic data
Statistical association networks as complex phenotypes in post-genomics
Statistical integration and visualisation of metabolic profiles with other post-genomic data
Time series analysis of post-genomic data