Thomas Kieran Sears - Department of Neurological Surgery, Northwestern University

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个人简介

Thomas Kieran Sears currently works at the Department of Neurological Surgery at Northwestern University. Thomas does research on Human Cancer Biology, Pharmacology, and Molecular Biology.

研究兴趣

论文共 23 篇作者统计合作学者相似作者

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The Novel DNA Cross-Linking Agent KL-50 is Active Against Patient-Derived Models of New and Recurrent Post-Temozolomide Mismatch Repair-Deficient Glioblastoma

Matthew McCord,Thomas Sears,Wenxia Wang, Rahul Chaliparambil,Shejuan An,Jann Sarkaria,C David James,Bruce Ruggeri,Susan Gueble,Ranjit Bindra,Craig Horbinski

Neuro-oncologyno. 3 (2025): 644-651

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LOCAL DELIVERY OF CHEMOTHERAPIES VIA BIORESORBABLE IMPLANT IN MENINGIOMAS

Mark Youngblood, Ziying Hu,Khizar Nandoliya,Vineeth Thirunavu,Wenxia Wang,Shejuan An,Matthew Mccord,Thomas Sears, Mateo Gomez,Anh Tran,Alicia Steffens,Jordain Walshon,Kathleen Mccortney, Mariah Flowers,Stephen Magill,John Rogers,Craig Horbinski

NEURO-ONCOLOGY (2024)

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NEW DNA-CROSSLINKING CHEMOTHERAPY IS EFFECTIVE AGAINST POST-TEMOZOLOMIDE MISMATCH REPAIR-DEFICIENT PATIENT-DERIVED HYPERMUTANT GLIOMAS

Matthew Mccord,Wenxia Wang,Shejuan An,Thomas Sears,Jann N. Sarkaria,C. David James, Bruce Ruggieri,Ranjit S. Bindra,Craig Horbinski

NEURO-ONCOLOGY (2024)

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PRECLINICAL TRIALS OF THE ANTIBODY-DRUG CONJUGATE TISOTUMAB VEDOTIN IN ADULT-TYPE DIFFUSE GLIOMAS

Thomas Sears,Wenxia Wang,Dusten Unruh,Alicia Steffens,Matthew Mccord,Craig Horbinski

NEURO-ONCOLOGY (2024)

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IMMU-54. THERAPEUTIC TARGETING OF STING IN MENINGIOMAS

Mark Youngblood,Shashwat Tripathi,Hinda Najem, Mateo Gomez,Nishanth Sadagopan,Thomas Sears,Lisa Hurley,Wenxia Wang, Harrshavasan Congivaram,Abrar Choudhury,Alicia Steffens,Daniel Oyon,Luis Fernandez, Ashley Selner,Jawad Fares, Matthew Hagan, Aaron Palmer, Constantine Karras, Joy Trybula,Peng Zhang,Alexander Stegh,Michael Curran,David Ashley,Stephen Magill,Craig Horbinski,James Chandler,Maciej Lesniak,Jason Miska,Gavin Dunn,David Raleigh,Amy Heimberger

Neuro-Oncologyno. Supplement_8 (2024)

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THERAPEUTIC TARGETING OF STING IN MENINGIOMAS

NEURO-ONCOLOGY (2024)

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EXTH-28. ISOCITRATE DEHYDROGENASE MUTATIONS PREDICT SENSITIVITY TO HISTONE DEACETYLASE INHIBITION AND ENHANCED HISTONE ACETYLATION DYNAMICS ONLY IN THE CONTEXT OF GLIOMA

Thomas Sears,Michael Drumm,Wenxia Wang,Craig Horbinski

NEURO-ONCOLOGY (2023)

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EXTH-25. EXPLOITING EPIGENETIC DYSREGULATION IN ISOCITRATE DEHYDROGENASE MUTANT GLIOMA VIA THE USE OF HISTONE DEACETYLASE INHIBITORS

Thomas Sears,Michael Drumm,Andrea Piunti,Craig Horbinski

NEURO-ONCOLOGY（2022）

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