Thomas N Williams
教授
Centre of African Research and Engagement
Institute of Global Health Innovation, Imperial College London;Malaria Network, Imperial College London;Section of Adult Infectious Disease, Department of Infectious Disease, Faculty of Medicine, Imperial College London;Department of Surgery & Cancer, Faculty of Medicine, Imperial College London
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个人简介
Tom's research group works on the positive and negative health consequences of a range of genetic disorders, with a particular focus on disorders affecting the red blood cell. They address this question through a range of approaches including large-scale epidemiological studies, health-economic studies, clinical trials, and laboratory-based studies that focus on the mechanisms of malaria resistance in children with defined red cell disorders. Examples of current projects include: a birth cohort study of more than 16,000 children, genotyped for a range of genetic polymorphisms, who are being followed for clinical events in Kilifi District, Kenya; descriptive studies of the natural history of sickle cell disease in East Africa; studies of the health consequences of a range of red cell disorders, and clinical trials in sick children, including two trials of hydroxyurea as a potential therapy in African children with sickle cell disease (REACH and H-PRIME).
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论文共 44 篇作者统计合作学者相似作者
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Sickle Cell Disease in Sub-Saharan Africapp.4-31, (2024)
The Lancet Haematologyno. 3 (2022): e172-e173
BMC Medicineno. 1 (2021): 1-2
Clinical infectious diseases : an official publication of the Infectious Diseases Society of Americano. 7 (2017): 939-946
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