Thomas J. Flotte, M.D., uses tissue-based approaches to understand melanoma. Specific areas of research interest include correlation of histology with patient outcomes, molecular alterations and biomarker expression. His research goals are to improve tumor diagnosis and develop new therapeutic strategies.

Dr. Flotte is also examining how technology can improve patient care. He is applying information technology and machine learning to assist pathologists in making better and more reproducible diagnoses. Additionally, he is working on cutting-edge technologies to provide new approaches and insights to the study of tissues to create better data that enhance the knowledge of diseases.