Thomas F. Gajewski

基本信息

Career Trajectory

Bio

Thomas Gajewski, MD, PhD, investigates and develops new treatments for patients with melanoma. He has a special interest in the development of immunotherapies against this disease. Dr. Gajewski also leads development of immune-based therapies for other cancers, using new laboratory data on how the immune system is regulated to develop novel clinical trials.

Dr. Gajewski serves as an editor for Cancer Research and Journal for Immunotherapy of Cancer. In addition, he is immediate past president of the Society for Immunotherapy of Cancer and has served on the program committees for the American Society for Clinical Oncology (ASCO) and the American Association for Cancer Research (AACR).

Research Interests

Papers共 655 篇Author StatisticsCo-AuthorSimilar Experts

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Neutralizing GDF-15 Can Overcome Anti-Pd-1 and Anti-Pd-l1 Resistance in Solid Tumours

Ignacio Melero, Maria de Miguel Luken,Guillermo de Velasco,Elena Garralda,Juan Martin-Liberal,Markus Joerger,Guzman Alonso,Maria-Elisabeth Goebeler,Martin Schuler,David Koenig,Reinhard Dummer,Maria Reig,Maria-Esperanza Rodriguez Ruiz,Emiliano Calvo,Jorge Esteban-Villarrubia,Arjun Oberoi, Paula Sabat,Juan Jose Soto-Castillo,Kira-Lee Koster,Omar Saavedra,Cyrus Sayehli,Tanja Gromke,Heinz Laeubli,Egle Ramelyte,Marta Fortuny, Ana Landa-Magdalena,Irene Moreno,Javier Torres-Jimenez,Alberto Hernando-Calvo,Dagmar Hess,Fabricio Racca,Heike Richly,Andreas M. Schmitt,Corinne Eggenschwiler,Marco Sanduzzi-Zamparelli,Anna Vilalta-Lacarra,Joerg Trojan,Christine Koch,Peter R. Galle,Friedrich Foerster,Zlatko Trajanoski,Hubert Hackl, Falk Gogolla,Florestan J. Koll,Peter Wild, Felix Kyoung Hwan Chun,Henning Reis,Peter Lloyd,Matthias Machacek,Thomas F. Gajewski,Wolf H. Fridman,Alexander M. M. Eggermont,Ralf Bargou,Sandra Schoeniger,Josef Rueschoff, Anastasiia Tereshchenko, Carina Zink, Antonio da Silva, Felix S. Lichtenegger, Julia Akdemir,Manfred Ruediger, Phil L'Huillier, Aradhana Dutta,Markus Haake, Alexandra Auckenthaler, Ana Gjorgjioska, Bernhard Roessler,Frank Hermann, Mara Liebig, Daniela Reichhardt,Christine Schuberth-Wagner,Joerg Wischhusen,Petra Fettes, Marlene Auer,Kathrin Klar,Eugen Leo

NATUREno. 8048 (2025)

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Author Correction: Neutralizing GDF-15 Can Overcome Anti-Pd-1 and Anti-Pd-l1 Resistance in Solid Tumours

Ignacio Melero, Maria de Miguel Luken,Guillermo de Velasco,Elena Garralda,Juan Martín-Liberal,Markus Joerger,Guzman Alonso,Maria-Elisabeth Goebeler,Martin Schuler,David König,Reinhard Dummer,Maria Reig,Maria-Esperanza Rodriguez Ruiz,Emiliano Calvo,Jorge Esteban-Villarrubia,Arjun Oberoi, Paula Sabat,Juan José Soto-Castillo,Kira-Lee Koster,Omar Saavedra,Cyrus Sayehli,Tanja Gromke,Heinz Läubli,Egle Ramelyte,Marta Fortuny, Ana Landa-Magdalena,Irene Moreno,Javier Torres-Jiménez,Alberto Hernando-Calvo,Dagmar Hess,Fabricio Racca,Heike Richly,Andreas M Schmitt,Corinne Eggenschwiler,Marco Sanduzzi-Zamparelli,Anna Vilalta-Lacarra,Jörg Trojan,Christine Koch,Peter R Galle,Friedrich Foerster,Zlatko Trajanoski,Hubert Hackl, Falk Gogolla,Florestan J Koll,Peter Wild, Felix Kyoung Hwan Chun,Henning Reis,Peter Lloyd,Matthias Machacek,Thomas F Gajewski,Wolf H Fridman, M,Ralf Bargou,Sandra Schöniger,Josef Rüschoff, Anastasiia Tereshchenko, Carina Zink, Antonio da Silva, Felix S Lichtenegger, Julia Akdemir,Manfred Rüdiger, Phil L'Huillier, Aradhana Dutta,Markus Haake, Alexandra Auckenthaler, Ana Gjorgjioska, Bernhard Rössler,Frank Hermann, Mara Liebig, Daniela Reichhardt,Christine Schuberth-Wagner,Jörg Wischhusen,Petra Fettes, Marlene Auer,Kathrin Klar,Eugen Leo

Nature (2025)

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Inherited Mitochondrial Genetics As a Predictor of Immune Checkpoint Inhibition Efficacy in Melanoma

Kelsey R Monson, Robert Ferguson, Joanna E Handzlik, Leah Morales, Jiahan Xiong, Vylyny Chat, Sasha Dagayev, Alireza Khodadadi-Jamayran,Danny Simpson,Esther Kazlow, Anabelle Bunis, Chaitra Sreenivasaiah, Milad Ibrahim,Iryna Voloshyna, Wouter Ouwerkerk,Rosalie M Luiten,Mariaelena Capone,Gabriele Madonna,Yuting Lu,Yongzhao Shao,Anna Pavlick,Michelle Krogsgaard,Janice Mehnert,Hao Tang, Sonia Dolfi,Daniel Tenney, John B A G Haanen,Thomas F Gajewski, F Stephen Hodi, Keith T Flaherty, Kasey Couts,William Robinson,Igor Puzanov, Marc S Ernstoff, Osama Rahma, Michael Postow, Ryan J Sullivan,Jason J Luke,Paolo A Ascierto, IO-GEM Consortium,Iman Osman,Tomas Kirchhoff

Nature medicine (2025)

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PKCδ Germline Variants and Genetic Deletion in Mice Augment Antitumor Immunity Through Regulation of Myeloid Cells

Kyle R Cron,Ayelet Sivan,Keston Aquino-Michaels,Andrea Ziblat,Emily F Higgs,Randy F Sweis, Ruxandra Tonea,Seoho Lee,Thomas F Gajewski

Cancer immunology research (2025)

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Tumor Cell-Intrinsic Decr2 Regulates Ferroptosis and Immunotherapy Efficacy

Shuyin Li, Jason W Shapiro,Hardik Shah, Emily F Higgs,Lishi Xie, Yaopeng Li,Yuanyuan Zha,Jonathan Trujillo,Alexandra Cabanov, Tyler A Jones,Blake Flood, Ken Hatogai, Ruxandra Tonea,Justin Kline,Thomas F Gajewski

Cancer immunology research (2025)

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Targeting Molecular Pathways to Control Immune Checkpoint Inhibitor Toxicities

Robin Reschke,Ryan J. Sullivan, Evan J. Lipson,Alexander H. Enk,Thomas F. Gajewski,Jessica C. Hassel

Trends in Immunology (2024)

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Decr2 Regulates Tumor Cell Ferroptosis and Immunotherapy Efficacy

Shuyin Li,Jason Shapiro,Hardik Shah,Emily F. Higgs,Lishi Xie,Yuanyuan Zha,Jonathan Trujillo,Alexandra Cabanov, Tyler A. Jones,Blake Flood,Ken Hatogai,Justin Kline,Thomas F. Gajewski

Cancer Research（2024）

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Batf3+ DCs and the 4-1BB/4-1BBL Axis Are Required at the Effector Phase in the Tumor Microenvironment for PD-1/PD-L1 Blockade Efficacy

Andrea Ziblat,Brendan L. Horton,Emily F. Higgs,Ken Hatogai,Anna Martinez,Jason W. Shapiro, Danny E. C. Kim,Yuanyuan Zha,Randy F. Sweis,Thomas F. Gajewski

Cell Reports（2024）

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Dendritic Cell-Intrinsic PTPN22 Negatively Regulates Antitumor Immunity and Impacts Anti-Pd-l1 Efficacy

Santiago Acero-Bedoya,Emily F. Higgs,Anna C. Martinez, Ruxandra Tonea,Thomas F. Gajewski

JOURNAL FOR IMMUNOTHERAPY OF CANCERno. 10 (2024)

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Papers共 655 篇Author StatisticsCo-AuthorSimilar Experts