Yoshimura's research focuses on the regulatory mechanisms of biological clock and signal transduction pathway regulating seasonal reproduction in vertebrates. The uniqueness of his research lies in the use of non-model animals and the systems biology approach. Most importantly, he has identified a "springtime hormone" that triggers seasonal reproduction and clarified the signal transduction cascade for animal seasonal reproduction. Yoshimura also identified a key gene regulating seasonal reproduction in birds, and later demonstrated that the discovered reproduction mechanism is conserved in seasonal mammalian species. These breakthrough findings became the basis of one of the core projects in ITbM. He will be involved mainly in the development of molecules that improve animal reproduction, collaborating with the groups of Ooi, Bode, Irle, and Itami.