基本信息
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个人简介
Dr. Wu’s research focuses on human papillomavirus (HPV) vaccine development.
He has created a unique preclinical murine tumor model that expresses HPV-16 oncogenic proteins (E6 and E7) and simulates specific molecular events in the progression of HPV+ precancerous lesions (CIN 3) to invasive cancer.
This model has been widely used and tested by researchers worldwide for HPV vaccine development.
Dr. Wu has focused on identifying immunotherapeutic and vaccine approaches to enhance antigen processing and presentation by dendritic cells. These include intracellular targeting and spreading strategies aimed at preventing and treating cervical lesions and cancers. Intracellular targeting directs antigens to different subcellular locations to enhance antigen processing and presentation.
研究兴趣
论文共 233 篇作者统计合作学者相似作者
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Brandon Lam,Yu Jui Kung,John Lin,Ssu-Hsueh Tseng, Hsin-Fang Tu, Claire Huang,Brandon Lee,Esteban Velarde,Ya Chea Tsai,Rafael Villasmil,Sung Taek Park,Deyin Xing,
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Scientific reportsno. 1 (2023): 18476-18476
Deyin Xing,Gang Zheng,Aparna Pallavajjala,J. Kenneth Schoolmeester,Yuehua Liu,Lisa Haley, Yan Hu, Li Liu, Lisa Logan, Yuan Lin,Kathryn E. Pearce, Christopher A. Sattler,
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Stephanie Gaillard,Jade Alvarez,Hao Wang,Hua-Ling Tsai, Amy Deery,Amanda Fader,Warner Huh,Rebecca Arend,Margaret Liang,J. Michael Straughn,T. C. Wu,Charles Leath,
GYNECOLOGIC ONCOLOGY (2023): S171-S172
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