My research interests and activities primarily focus on translational aspects of antimicrobial therapy of septic shock. In the past, I have also focused on a bench and bedside level at questions related to myocardial dysfunction in sepsis and septic shock. These latter studies continue with the co-operation of basic science investigators. More recent efforts have been focused basic and clinical aspects of pandemic (2009) H1N1 influenza and SARS-CoV-2 (COVID19) infection.