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Dr. Sui Huang is a molecular and cell biologist with a strong background in theoretical biology. He has devoted his research to understanding the very phenomenon of cancer from a complex systems perspective. Life scientists now readily acknowledge that the “whole is more than the sum of its parts” but the question is: What exactly is the “more” that we need in order to understand the “whole”? Can this abstract philosophical notion be reduced to a rigorous formal concept and concrete molecular entities? Pursuing this question has guided Dr. Huang‘s research in cancer and cell biology over the past decade.
Seeing how both interferons and anti-angiogenic agents have failed to live up to their celebrated promise of curing cancer has had a lasting impact on Dr. Huang’s views. The humbling recognition of the profound complexity of the living state fostered the desire to overcome the orthodoxy of reductionist, monocausal and deterministic thinking that prevailed in biomedicine and to put to use his knowledge of complex systems theory in his experimental research. Time was ripe in the late ’90s because the arrival of the “omics technologies” and systems biology paved the way towards this interdisciplinary approach. With his move to the ISB, Dr. Huang continues to unite experiment and theory to gain insights in the essence of multi-cellularity and cancer.
研究兴趣
论文共 215 篇作者统计合作学者相似作者
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Megan L Sulciner,Charles N Serhan,Molly M Gilligan, Dayna K Mudge,Jaimie Chang,Allison Gartung, Kristen A Lehner,Diane R Bielenberg, Birgitta Schmidt,Jesmond Dalli, Emily R Greene, Yael Gus-Brautbar,
The Journal of experimental medicineno. 3 (2024)
bioRxiv : the preprint server for biology (2024)
arxiv(2024)
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Sarina A. Virani, Michael Gillespie,Haixia Yang,Diane R. Bielenberg,Mark W. Kieran,Sui Huang,Charles N. Serhan,Dipak Panigrahy
Cancer Researchno. 6_Supplement (2024): 6817-6817
arxiv(2023)
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Yue Wang,Joseph X. Zhou,Edoardo Pedrini,Irit Rubin,May Khalil, Roberto Taramelli,Hong Qian,Sui Huang
JOURNAL OF THEORETICAL BIOLOGY (2023): 111645-111645
Gastroenterologyno. 2 (2023): 374-390
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Karamarie Fecho,Chris Bizon, Tursynay Issabekova,Sierra Moxon,Anne E Thessen, Shervin Abdollahi,Sergio E Baranzini, Basazin Belhu,William E Byrd, Lawrence Chung,Andrew Crouse,Marc P Duby,
Journal of clinical and translational scienceno. 1 (2023)
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Cancer Researchno. 12_Supplement (2022): 1329-1329
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