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The main focus of Dr. Srirams laboratory is to examine the immunological factor(s) which are likely involved in recovery of lesions from MS. Dr. Srirams laboratory discovered that one particular cytokine, IL-33 is an important player in promoting recovery in animal models of multiple sclerosis. Patients who have stable disease show increased levels of IL-33 in their blood and in the cerebrospinal fluid.
Dr. Srirams lab has also found certain novel genes that play a role in the induction of IL-33. In addition certain agents which have been used for multiple sclerosis in the past and since discarded may is likely to be a good candidate for promoting recovery.
Along with Drs Pawate and Bagnato, Dr. Sriram is interested in developing novel MRI techniques for examining recovery.
Dr. Srirams lab has also found certain novel genes that play a role in the induction of IL-33. In addition certain agents which have been used for multiple sclerosis in the past and since discarded may is likely to be a good candidate for promoting recovery.
Along with Drs Pawate and Bagnato, Dr. Sriram is interested in developing novel MRI techniques for examining recovery.
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REGULATORY TOXICOLOGY AND PHARMACOLOGY (2024): 105538-105538
MAGNETIC RESONANCE IMAGING (2024): 11-21
Journal of neuroimmunology (2023): 578219-578219
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Åsa Ljunggren-Rose,Chandramohan Natarajan, Pranathi Matta, Akansha Pandey, Isha Upender,Subramaniam Sriram
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