Stuart Aitken - 1Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh

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Stuart Aitken is a member of the University of Edinburgh's Artificial Intelligence Applications Institute. His research interests include ontology, bioinformatics, intelligent tools for knowledge acquisition, and machine learning. He received his PhD in computer science from the University of Glasgow. Contact him at the Artificial Intelligence Applications Inst., Univ. of Edinburgh, Appleton Tower, Crichton St., Edinburgh EH8 9LE, UK; stuart@aiai.ed.ac.uk.

Research Interests

Papers共 89 篇Author StatisticsCo-AuthorSimilar Experts

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Genetic Background Sets the Trajectory of Cancer Evolution

Sarah J Aitken,Frances Connor,Christine Feig,Tim F Rayner,Margus Lukk,Juliet Luft,Stuart Aitken,Claudia Arnedo-Pac, James F Hayes,Michael D Nicholson,Vasavi Sundaram, Jan C Verburg,John Connelly,Craig J Anderson,Mikaela Behm,Susan Campbell,Maelle Daunesse,Ailith Ewing,Vera B Kaiser,Elissavet Kentepozidou,Oriol Pich,Aisling M Redmond,Javier Santoyo-Lopez,Ines Sentis,Lana Talmane, Liver Cancer Evolution Consortium,Paul Flicek, Nuria Lopez-Bigas,Colin A Semple,Martin S Taylor,Duncan T Odom

biorxiv（2025）

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Tumour Suppressor WT1 and Its Interacting Protein RNA Helicase DDX5 Regulate the Microrna Let7/igf1r Axis in the Kidney Mesenchyme

Sourav Dey,Joan Slight,Stuart Aitken, Iwin Joseph, Utkarsh Bhore, Alex vonkriegsheim, Giulia Petrovich,Jocelyn Charlton,Viktoriya Stancheva, Debasis Mohapatra,Abdelkader Essafi,Kathy Pritchard Jones,Nicholas Hastie, Ruthrotha Selvi Bharathavikru

biorxiv（2025）

Cited0Views0Bibtex

Divergent Trajectories to Structural Diversity Impact Patient Survival in High Grade Serous Ovarian Cancer

Ailith Ewing,Alison Meynert, Ryan Silk,Stuart Aitken,Devin P. Bendixsen,Michael Churchman, Stuart L. Brown,Alhafidz Hamdan, Joanne Mattocks,Graeme R. Grimes,Tracy Ballinger,Robert L. Hollis,C. Simon Herrington,John P. Thomson,Kitty Sherwood, Thomas Parry, Edward Esiri-Bloom,Clare Bartos,Ian Croy,Michelle Ferguson,Mairi Lennie,Trevor McGoldrick,Neil McPhail,Nadeem Siddiqui,Rosalind Glasspool,Melanie Mackean,Fiona Nussey,Brian McDade,Darren Ennis, The Scottish Genomes Partnership,Lynn McMahon,Athena Matakidou,Brian Dougherty,Ruth March,J. Carl Barrett,Iain A. McNeish,Andrew V. Biankin,Patricia Roxburgh,Charlie Gourley,Colin A. Semple

biorxiv（2024）

Cited2Views0Bibtex

The V-ATPase Complex Component RNAseK is Required for Lysosomal Hydrolase Delivery and Autophagosome Degradation

Agata N. Makar, Alina Boraman,Peter Mosen,Joanne E. Simpson, Jair Marques, Tim Michelberger,Stuart Aitken,Ann P. Wheeler,Dominic Winter,Alex von Kriegsheim,Noor Gammoh

NATURE COMMUNICATIONSno. 1 (2024)

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Ciliopathy Patient Variants Reveal Organelle-Specific Functions for TUBB4B in Axonemal Microtubules

Daniel O. Dodd,Sabrina Mechaussier,Patricia L. Yeyati,Fraser McPhie,Jacob R. Anderson, Chen Jing Khoo,Amelia Shoemark,Deepesh K. Gupta,Thomas Attard,Maimoona A. Zariwala,Marie Legendre,Diana Bracht,Julia Wallmeier,Miao Gui,Mahmoud R. Fassad,David A. Parry,Peter A. Tennant,Alison Meynert,Gabrielle Wheway,Lucas Fares-Taie,Holly A. Black,Rana Mitri-Frangieh,Catherine Faucon,Josseline Kaplan,Mitali Patel,Lisa McKie,Roly Megaw,Christos Gatsogiannis,Mai A. Mohamed,Stuart Aitken,Philippe Gautier, Finn R. Reinholt,Robert A. Hirst,Chris O'Callaghan,Ketil Heimdal,Mathieu Bottier,Estelle Escudier,Suzanne Crowley,Maria Descartes,Ethylin W. Jabs,Priti Kenia,Jeanne Amiel,Giacomo Maria Bacci,Claudia Calogero,Viviana Palazzo,Lucia Tiberi,Ulrike Bluemlein,Andrew Rogers,Jennifer A. Wambach,Daniel J. Wegner,Anne B. Fulton,Margaret Kenna,Margaret Rosenfeld,Ingrid A. Holm,Alan Quigley,Emma A. Hall,Laura C. Murphy,Diane M. Cassidy,Alex von Kriegsheim,Jean-Francois Papon,Laurent Pasquier,Marlene S. Murris,James D. Chalmers,Claire Hogg,Kenneth A. Macleod,Don S. Urquhart,Stefan Unger,Timothy J. Aitman,Serge Amselem,Margaret W. Leigh,Michael R. Knowles,Heymut Omran,Hannah M. Mitchison,Alan Brown,Joseph A. Marsh,Julie P. I. Welburn,Shih-Chieh Ti,Amjad Horani,Jean-Michel Rozet,Isabelle Perrault,Pleasantine Mill

SCIENCEno. 6694 (2024)

Cited10Views0WOSSCIENCEBibtex

11Β-Hsd1 Inhibition Does Not Affect Murine Tumour Angiogenesis but May Exert a Selective Effect on Tumour Growth by Modulating Inflammation and Fibrosis

Callam T. Davidson,Eileen Miller,Morwenna Muir,John C. Dawson,Martin Lee,Stuart Aitken,Alan Serrels,Scott P. Webster,Natalie Z. M. Homer,Ruth Andrew,Valerie G. Brunton,Patrick W. F. Hadoke,Brian R. Walker

PLOS ONE（2023）

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Genomic Diagnosis of Rare Pediatric Disease in the United Kingdom and Ireland

NEW ENGLAND JOURNAL OF MEDICINEno. 17 (2023): 1559-1571

Cited70Views0WOSBibtex

IMPROVE-DD: Integrating Multiple Phenotype Resources Optimizes Variant Evaluation in Genetically Determined Developmental Disorders

Stuart Aitken,Helen Firth,Caroline F. Wright,Matthew E. Hurles,David R. FitzPatrick,Colin A. Semple

HUMAN GENETICS AND GENOMICS ADVANCESno. 1 (2023)

Cited2Views0WOSBibtex

A Dual Role for the RNA Helicase DHX34 in NMD and Pre-Mrna Splicing and Its Function in Hematopoietic Differentiation

Nele Hug,Stuart Aitken,Dasa Longman, Michaela Raab,Hannah Armes,Abigail R. Mann,Ana Rio-Machin,Jude Fitzgibbon,Kevin Rouault-Pierre,Javier F. Caceres

RNA（2022）

Cited6Views0WOSBibtex

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