His research interests are primarily in the area of GI cancer genetics and he is co-Director of the Centre for Cancer Genetics at the Samuel Lunenfeld Research Institute, and co-PI of the Zane Cohen Familial Gastrointestinal Cancer Registry at MSH.

He is also PI of the Ontario Pancreas Cancer Study, a member of the NIH funded Pancreas Cancer Genetic Epidemiology consortium, a population-based registry of pancreas cancer cases and their families which is now integrated with the International Cancer Genome Consortium at the OICR where he is Head of the Translational Research Initiative in pancreas cancer, termed PanCuRx.