基本信息
浏览量:6
职业迁徙
个人简介
I am a pharmacologist interested in unraveling the biological effects of endogenous modulators and natural products on the host inflammatory response and cell protection and have supervised 12 students to completion of their PhD. My main interest is understanding the role played by the melanocortin peptides and natural products. The aim of this research is to understand their mechanism of action of these compounds and identification of the target receptors for pharmacological manipulation and subsequent disease treatment. Understanding how these naturally occurring anti-inflammatory agents exhibit a dual mechanism of action i.e. an early phase inhibition of cytokine release and a late induction of pro-resolving pathways is an exciting development. This research will hopefully lead to development of novel therapeutics to treat some of the biggest debilitating diseases that we face including arthritis and cerebral ischaemia. At present my main research areas involve looking at the biological effects of these peptides and natural products in human osteoarthritic cell-lines and in models of neuroinflammation and neuroprotection.
研究兴趣
论文共 48 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
International Journal of Molecular Sciencesno. 21 (2023): 15996-15996
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn