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Research within the Davies group is concerned with investigations into a wide variety of topics including the development of new synthetic methodology, catalysis, mechanistic investigations, total synthesis and collaborative projects in medicinal chemistry. For example, this includes new applications for the conjugate addition of enantiopure lithium amides, development of kinetic resolution processes for the preparation of functionalised molecular building blocks, new methods for nucleophilic fluorination, methodology for the chemoselective functionalisation of unsaturated amines at the olefin (rather than the nitrogen atom), and application of these methodologies to the total synthesis of natural products of biological significance (including pyrrolidines, piperidines, tropanes, pyrrolizidines, and imino- and aminosugars).
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Organic & biomolecular chemistryno. 42 (2023): 8535-8547
Laia Josa-Culleré,Sébastien R.G. Galan,Thomas J. Cogswell,Thomas R. Jackson,Morgan Jay-Smith, Laura Mola, Christopher R. Greaves,Tom S. Carter,Katrina S. Madden,Sophie Trott,Douzi Zhang,Carole J.R. Bataille,
European Journal of Medicinal Chemistry (2023): 115509-115509
Steven Westwood,Katrice Lippa, Yoshitaka Shimuzu, Beatrice Lalerle,Takeshi Saito,David Duewer,Xinhua Dai,Stephen Davies, Marina Ricci,Annarita Baldan,Brian Lang, Stefan Sarge,
PURE AND APPLIED CHEMISTRYno. 1 (2023): 1-77
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Organic & Biomolecular Chemistryno. 13 (2021): 2847-2855
Thomas R. Jackson,Aini Vuorinen,Laia Josa-Culleré,Katrina S. Madden,Daniel Conole,Thomas J. Cogswell,Isabel V. L. Wilkinson, Laura M. Kettyle,Douzi Zhang, Alison O’Mahony,Deanne Gracias, Lorna McCall,
biorxiv(2021)
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