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Research Summary
The goal of our laboratory is to develop more efficacious treatments for alcohol use disorders and nicotine dependence and to provide the science base for the regulation of tobacco products. Toward this end, we are conducting clinical trials to determine efficacy of medications and behavioral interventions, and laboratory studies to determine the mechanisms underlying the effects of treatment and the underlying nature of the disorder. Research on how flavors, such as methol and sweeteners, influence the use of tobacco products is underway to inform the regulation of tobacco products by the FDA.
Specialized Terms: Medications development for alcoholism and smoking; Risk reduction and young adult drinking; tobacco regulatory science; treatment methodology; patient treatment matching; biomarkers of treatment response
Extensive Research Description
Yale Tobacco Center for Regulatory Science
Clinical trials of varenicline for the treatment of alcohol dependence among smokers and of naltrexone for young adult heavy drinkers
Laboratory studies to evaluate medications for substance use disorders
Validation of biomarkers for monitoring drinking in clinical trials
Secondary analyses to identify moderators and predictors of response to treatments for alcohol dependence using tree based and trajectory analyses
Training of clinician and transdisciplinary scientists
Research Interests
Alcoholism; Psychiatry; Smoking; Substance-Related Disorders; Risk Reduction Behavior; Psychiatry and Psychology
The goal of our laboratory is to develop more efficacious treatments for alcohol use disorders and nicotine dependence and to provide the science base for the regulation of tobacco products. Toward this end, we are conducting clinical trials to determine efficacy of medications and behavioral interventions, and laboratory studies to determine the mechanisms underlying the effects of treatment and the underlying nature of the disorder. Research on how flavors, such as methol and sweeteners, influence the use of tobacco products is underway to inform the regulation of tobacco products by the FDA.
Specialized Terms: Medications development for alcoholism and smoking; Risk reduction and young adult drinking; tobacco regulatory science; treatment methodology; patient treatment matching; biomarkers of treatment response
Extensive Research Description
Yale Tobacco Center for Regulatory Science
Clinical trials of varenicline for the treatment of alcohol dependence among smokers and of naltrexone for young adult heavy drinkers
Laboratory studies to evaluate medications for substance use disorders
Validation of biomarkers for monitoring drinking in clinical trials
Secondary analyses to identify moderators and predictors of response to treatments for alcohol dependence using tree based and trajectory analyses
Training of clinician and transdisciplinary scientists
Research Interests
Alcoholism; Psychiatry; Smoking; Substance-Related Disorders; Risk Reduction Behavior; Psychiatry and Psychology
研究兴趣
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Molecular Psychiatryno. 8 (2023): 3384-3390
Addictive Behaviors (2023): 107753-107753
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Madilyn M. Augustine,Garrett I. Ash,Kelly S. DeMartini,Stephanie O'Malley, Adrian A. Haughton,Lisa M. Fucito
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ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCHno. 12 (2022): 2258-2266
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