Over the past 30+ years, I have applied my engineering background to interdisciplinary biomedical research, including mathematical and biophysical modelling, measurement systems and methods design, direct clinical measurements, imaging and estimation using PET, SPECT, and MR, and the clinical and self-assessment approaches. Applications include wide range of clinical specialties in Neurosciences (Neurosurgery, Neurology and Psychiatry), Dermatology, Cardiovascular and Internal Medicine.