Stefaan Last

Janssen Infectious Diseases Diagnostics BVBA

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论文共 12 篇作者统计合作学者相似作者

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Enabling Deoxygenative C(sp2)-C(sp3) Cross-Coupling for Parallel Medicinal Chemistry

Wei Liu,James Mulhearn,Bo Hao,Santiago Canellas,Stefaan Last,Jose Enrique Gomez, Alexander Jones, Alexander De Vera,Kiran Kumar,Raquel Rodriguez, Lars Van Eynde,Iulia I. Strambeanu,Scott E. Wolkenberg

ACS MEDICINAL CHEMISTRY LETTERS（2023）

引用9浏览0WOS引用

Discovery of Selective 2,4-Diaminoquinazoline Toll-Like Receptor 7 (TLR 7) Agonists

Serge Pieters,David McGowan,Florence Herschke,Frederik Pauwels,Bart Stoops,Stefaan Last,Werner Embrechts,Annick Scholliers,Wendy Mostmans,Kris Van Dijck,Bertrand Van Schoubroeck,Tine Thone,Dorien De Pooter,Gregory Fanning, Mari Luz Rosauro,Mourad Daoubi Khamlichi,Ioannis Houpis,Eric Arnoult,Tim H. M. Jonckers,Pierre Raboisson

Bioorganic & Medicinal Chemistry Letters（2018）

引用14浏览0WOS引用

2,4-Diaminoquinazolines As Dual Toll-like Receptor (TLR) 7/8 Modulators for the Treatment of Hepatitis B Virus

Werner Embrechts,Florence Herschke,Frederik Pauwels,Bart Stoops,Stefaan Last,Serge Pieters,Vineet Pande,Geert Pille,Katie Amssoms,Ilham Smyej,Deborah Dhuyvetter,Annick Scholliers,Wendy Mostmans,Kris Van Dijck,Bertrand Van Schoubroeck,Tine Thone,Dorien De Pooter,Gregory Fanning,Tim H. M. Jonckers,Helen Horton,Pierre Raboisson,David McGowan

Journal of Medicinal Chemistry（2018）

引用25浏览0WOS引用

Characterization of a Dengue NS4B Inhibitor Originating from an HCV Small Molecule Library

Ilane Hernandez-Morales,Peggy Geluykens,Marleen Clynhens,Rudy Strijbos,Olivia Goethals,Sarah Megens,Nick Verheyen,Stefaan Last,David McGowan,Erwin Coesemans,Benoit De Boeck,Bart Stoops,Benoit Devogelaere,Frederik Pauwels,Koen Vandyck,Jan Martin Berke,Pierre Raboisson,Kenneth Simmen,Pedro Lory,Marnix Van Loock

Antiviral Research（2017）

引用17浏览0WOS引用

Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B

David C. McGowan,Florence Herschke,Frederik Pauwels,Bart Stoops,Ilham Smyej,Stefaan Last,Serge Pieters,Werner Embrechts,Mourad Daoubi Khamlichi,Tine Thone,Bertrand Van Schoubroeck,Wendy Mostmans, Debbie Wuyts,Dorien Verstappen,Annick Scholliers,Dorien De Pooter,Deborah Dhuyvetter,Herman Borghys,Marianne Tuefferd,Eric Arnoult,Jin Hong,Gregory Fanning,Jacques Bollekens,Vijay Urmaliya,Ard Teisman,Helen Horton,Tim H. M. Jonckers,Pierre Raboisson

Journal of Medicinal Chemistry（2017）

引用18浏览0WOS引用

Novel Pyrimidine Toll-like Receptor 7 and 8 Dual Agonists to Treat Hepatitis B Virus

David McGowan,Florence Herschke,Frederik Pauwels,Bart Stoops,Stefaan Last,Serge Pieters,Annick Scholliers,Tine Thoné,Bertrand Van Schoubroeck,Dorien De Pooter,Wendy Mostmans,Mourad Daoubi Khamlichi,Werner Embrechts,Deborah Dhuyvetter,Ilham Smyej,Eric Arnoult,Samuël Demin,Herman Borghys,Gregory Fanning,Jaromir Vlach,Pierre Raboisson

JOURNAL OF MEDICINAL CHEMISTRY（2016）

引用36浏览0WOS引用

Discovery and Early Development of TMC647055, a Non-Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase

Maxwell D. Cummings,Tse-I Lin,Lili Hu,Abdellah Tahri,David McGowan,Katie Amssoms,Stefaan Last,Benoit Devogelaere,Marie-Claude Rouan,Leen Vijgen,Jan Martin Berke,Pascale Dehertogh,Els Fransen,Erna Cleiren,Liesbet van der Helm,Gregory Fanning,Origene Nyanguile,Kenny Simmen,Pieter Van Remoortere,Pierre Raboisson,Sandrine Vendeville

Journal of medicinal chemistry（2013）

引用35浏览0WOS引用

Finger-loop Inhibitors of the HCV NS5b Polymerase. Part 1: Discovery and Optimization of Novel 1,6- and 2,6-Macrocyclic Indole Series

David McGowan,Sandrine Vendeville,Tse-I Lin,Abdellah Tahri,Lili Hu,Maxwell D. Cummings,Katie Amssoms,Jan Martin Berke,Maxime Canard,Erna Cleiren,Pascale Dehertogh,Stefaan Last,Els Fransen,Elisabeth Van der Helm,Iris Van den Steen,Leen Vijgen,Marie-Claude Rouan,Gregory Fanning,Origene Nyanguile,Kristof Van Emelen,Kenneth Simmen,Pierre Raboisson

Bioorganic & Medicinal Chemistry Letters（2012）

引用20浏览0WOS引用

Finger Loop Inhibitors of the Hcv Ns5b Polymerase. Part Ii. Optimization of Tetracyclic Indole-Based Macrocycle Leading to the Discovery of Tmc647055

Sandrine Vendeville,Tse-I Lin,Lili Hu,Abdellah Tahri,David McGowan,Maxwell D. Cummings,Katie Amssoms,Maxime Canard,Stefaan Last,Iris Van den Steen,Benoit Devogelaere,Marie-Claude Rouan,Leen Vijgen,Jan Martin Berke,Pascale Dehertogh,Els Fransen,Erna Cleiren,Liesbet Van der Helm,Gregory Fanning,Kristof Van Emelen,Origene Nyanguile,Kenny Simmen,Pierre Raboisson

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2012）

引用40浏览0WOS引用

Structure‐Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties

Maxwell D. Cummings,Tse-I Lin,Lili Hu,Abdellah Tahri,David McGowan,Katie Amssoms,Stefaan Last,Benoit Devogelaere,Marie-Claude Rouan,Leen Vijgen,Jan Martin Berke,Pascale Dehertogh,Els Fransen,Erna Cleiren,Liesbet van der Helm,Gregory Fanning,Kristof Van Emelen,Origene Nyanguile,Kenny Simmen,Pierre Raboisson,Sandrine Vendeville

Angewandte Chemie（2012）

引用34浏览0WOS引用

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作者统计

#Papers: 12

#Citation: 365

H-Index: 11

G-Index: 12

Sociability: 4

Diversity: 2

Activity: 1

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