Research Synopsis
The goal of the Tripathy Lab is to develop a multi-scale understanding of brain cell type diversity, bridging genetics and gene expression with cell and circuit physiology. The lab develops machine learning and statistical methods to help neuroscientists translate information at different levels of organization, like gene expression to neuron electrophysiology. The long-term goal of this work is to better understand the cellular changes that underlie psychiatric and neurological disorders and to ultimately develop approaches that can help guide tailored treatments for mental health patients.
The lab is part of the new Krembil Centre for Neuroinformatics and contributes to the building of large-scale computational simulations of the nervous system. The lab is a computational “dry-lab”, but collaborates extensively with experimental groups in Toronto and beyond.