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A major focus of my research has been on understanding the role(s) of the growth hormone (GH) and its downstream regulator insulin-like growth factor-1 (IGF-1) in tissue growth, development and repair. In particular, our research focuses on skeletal acquisition and maintenance of bone mass during growth and aging, respectively. We have generated numerous mouse models of global and tissue-specific ablation of the different members of the GH/IGF-1 axis and characterize their skeletal development.
A major focus of my research has been on understanding the role(s) of the growth hormone (GH) and its downstream regulator insulin-like growth factor-1 (IGF-1) in tissue growth, development and repair. In particular, our research focuses on skeletal acquisition and maintenance of bone mass during growth and aging, respectively. We have generated numerous mouse models of global and tissue-specific ablation of the different members of the GH/IGF-1 axis and characterize their skeletal development.
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论文共 44 篇作者统计合作学者相似作者
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JOURNAL OF BONE AND MINERAL RESEARCH (2023): 59-60
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Manisha Dixit,Leeann D Louis,Jelena Basta-Pljakic,Gozde Yildirim,Sher-Bahadur Poudel, Fancy Kumararaja,Edward O List, Silvana Ortiz Duran,John J Kopchick,Ryan R Ruff,Mitchell B Schaffler,Shoshana Yakar
Molecular and Cellular Endocrinology (2021): 111052-111052
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