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My research interest is to understand the molecular basis of neural circuitry that translates sensory inputs into behavioral outputs. At the Allen Institute, I will contribute to the development of viral vector tools that enable us to mark and trace the connectivities from molecularly defined populations of neurons. On the basis of anatomical dissection of circuit connectivity, I will also develop tools that will allow functional perturbation of distinct circuit components by combining genetic engineering with optogenetics and chemogenetics. Development and optimization of the above tools will facilitate the ongoing effort of the Allen Institute in characterizing different cell types in the brain and understanding the nature of the connections between cells of various types.
My research interest is to understand the molecular basis of neural circuitry that translates sensory inputs into behavioral outputs. At the Allen Institute, I will contribute to the development of viral vector tools that enable us to mark and trace the connectivities from molecularly defined populations of neurons. On the basis of anatomical dissection of circuit connectivity, I will also develop tools that will allow functional perturbation of distinct circuit components by combining genetic engineering with optogenetics and chemogenetics. Development and optimization of the above tools will facilitate the ongoing effort of the Allen Institute in characterizing different cell types in the brain and understanding the nature of the connections between cells of various types.
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论文共 33 篇作者统计合作学者相似作者
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John K Mich,Smrithi Sunil,Nelson Johansen,Refugio A Martinez, Mckaila Leytze,Bryan B Gore,Joseph T Mahoney, Yoav Ben-Simon,Yemeserach Bishaw,Krissy Brouner,Jazmin Campos,Ryan Canfield,
bioRxiv : the preprint server for biology (2023)
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Science (New York, N.Y.)no. 6576 (2022): 41-+
NEURONno. 23 (2022): 3986-+
John K. Mich,Bryan B. Gore,Refugio A. Martinez, Mckaila Leytze,Joseph T. Mahoney,Yemeserach Bishaw,Victoria Omstead, Deja Machen, Naz Taskin,Natalie Weed,Ximena Opitz-Araya,Nick Dee,
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