基本信息
浏览量:52
职业迁徙
个人简介
We are interested in understanding the intrinsic mechanisms of mechanosensitive ion channels, the primary receptor molecules that convert mechanical forces into electrical or chemical signals in cells. Such channels are found in many types of sensory and non-sensory cells in vertebrates, as well as in many groups of organisms across the Tree of Life, including Bacteria and Archaea. Mechanosensitive channels are diverse and may include several unrelated groups of membrane proteins.
Our current research focuses on bacterial mechanosensitive channels MscL and MscS, which function as osmolyte release valves in prokaryotes. These channels are good models for studies of basic principles of membrane-based sensory mechanisms because they gate directly in response to tension in the lipid bilayer, and their crystal structures are available.
Our current research focuses on bacterial mechanosensitive channels MscL and MscS, which function as osmolyte release valves in prokaryotes. These channels are good models for studies of basic principles of membrane-based sensory mechanisms because they gate directly in response to tension in the lipid bilayer, and their crystal structures are available.
研究兴趣
论文共 201 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
biorxiv(2024)
bioRxiv : the preprint server for biology (2024)
crossref(2024)
bioRxiv : the preprint server for biology (2024)
Биологические мембраны Журнал мембранной и клеточной биологииno. 1 (2023): 19-42
Wai-Kin Chan,Thomas D. Horvath,Lin Tan,Todd Link,Karine G. Harutyunyan,Michael A. Pontikos,Andriy Anishkin,Di Du, Leona A. Martin, Eric Yin,Susan B. Rempe,Sergei Sukharev,
crossref(2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn