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个人简介
Professor Ylä-Herttuala runs a world leading laboratory in cardiovascular and malignant glioma gene therapy. Main focus of the research is on the development of new gene drugs, translational research and phase I/II human clinical trials.
The main focus of the research is on the development of new gene therapy approaches for cardiovascular diseases, malignant glioma and diseases caused by disturbances in vascular biology. Virus-derived gene transfer vectors, cloning of new treatment genes and the use of genetic information for therapeutic purposes form the main research activities in the group. Also, translational research and clinical phase I/II human studies are conducted with vectors and treatment genes developed in the group. So far, we have conducted eight phase I/II/III clinical studies with vectors developed and produced in the National Virus Vector Laboratory located in A.I. Virtanen Institute, University of Eastern Finland.
The main focus of the research is on the development of new gene therapy approaches for cardiovascular diseases, malignant glioma and diseases caused by disturbances in vascular biology. Virus-derived gene transfer vectors, cloning of new treatment genes and the use of genetic information for therapeutic purposes form the main research activities in the group. Also, translational research and clinical phase I/II human studies are conducted with vectors and treatment genes developed in the group. So far, we have conducted eight phase I/II/III clinical studies with vectors developed and produced in the National Virus Vector Laboratory located in A.I. Virtanen Institute, University of Eastern Finland.
研究兴趣
论文共 1011 篇作者统计合作学者相似作者
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Ibrahim Sultan, Markus Ramste, Pim Peletier, Karthik Amudhala Hemanthakumar,Deepak Ramanujam, Annakaisa Tirronen, Ylva von Wright,Salli Antila, Pipsa Saharinen,Lauri Eklund, Eero Mervaala,Seppo Ylä-Herttuala,
Circulation research (2024)
Giuseppe Mocci,Katyayani Sukhavasi,Tiit Örd,Sean Bankier,Prosanta Singha,Uma Thanigai Arasu, Olayinka Oluwasegun Agbabiaje,Petri Mäkinen,Lijiang Ma,Chani J Hodonsky,Redouane Aherrahrou,Lars Muhl,
Circulation research (2024)
biorxiv(2024)
ALZHEIMERS & DEMENTIAno. 2 (2024): 954-974
Cardiorenal medicine (2024)
Cardiovascular research (2024)
Santeri Tarvainen, Galina Wirth,Greta Juusola, Olli Hautero,Kari Kalliokoski,Tanja Sjoros,Veikko Nikulainen,Jouni Taavitsainen,Jarkko Hytonen,Crister Frimodig,Krista Happonen,Tuomas Selander,
Jaakko Lampela, Juho Pajula,Niko Järveläinen,Satu Siimes,Nihay Laham-Karam,Antti Kivelä,Isidore Mushimiyimana,Jussi Nurro,Juha Hartikainen,Seppo Ylä-Herttuala
Scientific Reportsno. 1 (2024): 1-10
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