His research interests include the design of bio-inspired polymers for biomaterials and pharmaceutical develoment, especially based on polypeptide, proteins and polysaccharide-based block copolymers self-assembly, the design of polymersomes for drug-delivery and theranostic, as well as biomimetic approaches toward design of synthetic viruses and artificial cells. He published over 220 publications in international journal, 6 book chapters and 12 patents (3 being licenced), with over 18000 citations (h-factor 67, Google Scholar). He is also co-director of the joint laboratory LCPO-L'OREAL. Sébastien Lecommandoux is recipient of the CNRS bronze medal (2004), Institut Universitaire de France Junior Chair (IUF 2007), Fellow of the Royal Society of Chemistry RSC (2017), Seqens Award of the French Academy of Science (2019), Member of the Academia Europaea (2020), XingDa Lectureship Award from Peking University (2021). He has been Editor-in-Chief of Biomacromolecules (ACS) since 2020 after serving as Associate Editor since 2013. He is also in the Editorial Advisory Board of several international journals, including Bioconjugate Chemistry (ACS), Polymer Chemistry (RSC) and Biomaterials Science (RSC).