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职业迁徙
个人简介
My research revolves around microbe-induced host cell reprogramming by effector proteins that are shuttled into plant cells. Effectors are a hallmark for animal and plant pathogens’ success in conquering the host. Plant populations frequently maintain counter-defensive disease resistance proteins (R proteins) for intracellular recognition of effectors. Studying R protein mechanisms thus reveals plant strategies in coping with constant pathogen challenge.
During my masters and Ph.D. studies with Thomas Lahaye in Halle I characterised the tomato TIR-NB-LRR protein Bs4. Bs4 confers resistance towards the bacterial pathogen Xanthomonas campestris pv vesicatoria. Xanthomonads are the causal agents of economically important bacterial plant diseases in tomato, pepper, citrus and rice. Tomato Bs4-mediated resistance is achieved by cytoplasmic recognition of a set of Xanthomonas-translocated transcription activator-like (TAL) effector proteins.
During my masters and Ph.D. studies with Thomas Lahaye in Halle I characterised the tomato TIR-NB-LRR protein Bs4. Bs4 confers resistance towards the bacterial pathogen Xanthomonas campestris pv vesicatoria. Xanthomonads are the causal agents of economically important bacterial plant diseases in tomato, pepper, citrus and rice. Tomato Bs4-mediated resistance is achieved by cytoplasmic recognition of a set of Xanthomonas-translocated transcription activator-like (TAL) effector proteins.
研究兴趣
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Enoch Lok Him Yuen,Yasin Tumtas, Lok I Chan, Tarhan Ibrahim,Edouard Evangelisti,Frej Tulin,Jan Sklenar,Frank Menke,Sophien Kamoun,Doryen Bubeck,Sebastian Schornack,Tolga O Bozkurt
biorxiv(2024)
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CURRENT BIOLOGYno. 4 (2024): 793-807.e7
The Plant cell (2024)
Proceedings of the National Academy of Sciencesno. 41 (2023)
New Phytologistno. 3 (2023): 1127-1139
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Cell Host & Microbeno. 5 (2023): 683-684
Trends in plant science (2023)
Chloe Beaulieu,Cyril Libourel, Duchesse-Lacours Mbadinga Zamar,Karima El Mahboubi,David J. Hoey,Jean Keller, Camille Girou,Helene San Clemente, Issa Diop,Emilie Amblard, Anthony Theron,Stephane Cauet,
biorxiv(2023)
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Proceedings of the National Academy of Sciences of the United States of Americano. 41 (2023)
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