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Research
Dr. Murphy’s work focuses on the immune response to complex infectious diseases and on diagnostic test development. The major focus of the laboratory is malaria infection of humans and animal models by Plasmodium parasites. Using novel high-throughput T cell screening technologies developed in collaboration with Dr. Brad Stone, Dr. Murphy’s group studies the complex poly-specific T cell repertoire induced by Plasmodium sporozoites using mouse models of malaria infection. The laboratory is also exploring novel methods to experimentally induce broadly protective immune responses against malaria using synthetic biology-based T cell vaccines.
Dr. Murphy’s work focuses on the immune response to complex infectious diseases and on diagnostic test development. The major focus of the laboratory is malaria infection of humans and animal models by Plasmodium parasites. Using novel high-throughput T cell screening technologies developed in collaboration with Dr. Brad Stone, Dr. Murphy’s group studies the complex poly-specific T cell repertoire induced by Plasmodium sporozoites using mouse models of malaria infection. The laboratory is also exploring novel methods to experimentally induce broadly protective immune responses against malaria using synthetic biology-based T cell vaccines.
研究兴趣
论文共 168 篇作者统计合作学者相似作者
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Dianna Hergott,Carlos Guerra,Guillermo García, Jeremías Nzamio, Olivier Donfack, Marcos Mbulito Iyanga, Restituto Mba Nguema, Crisantos Nsue Abeso, Teresa Ayingono Ondo Mfumu, Matilde Riloha Rivas, Wonder Phiri,Sean Murphy,
crossref(2024)
Dianna E. B. Hergott, Tonny J. Owalla,Weston J. Staubus,Annette M. Seilie,Chris Chavtur,Jennifer E. Balkus, Bernadette Apio, Jimmy Lema, Barbara Cemeri, Andrew Akileng,Ming Chang,Thomas G. Egwang,
Debashree Goswami,Hardik Patel, William Betz, Janna Armstrong,Nelly Camargo,Asha Patil,Sumana Chakravarty,Sean C Murphy,B Kim Lee Sim,Ashley M Vaughan, Stephen L Hoffman,Stefan Hi Kappe
EMBO molecular medicineno. 4 (2024): 723-754
Felicia N. Watson,Melanie J. Shears,Anya C. Kalata,Caroline J. Duncombe, A. Mariko Seilie,Chris Chavtur, Ethan Conrad,Irene Cruz Talavera,Andrew Raappana,D. Noah Sather,Sumana Chakravarty,B. Kim Lee Sim,
Scientific Reportsno. 1 (2024): 1-16
Kassoum Kayentao,Aissata Ongoiba,Anne C Preston, Sara A Healy,Zonghui Hu,Jeff Skinner,Safiatou Doumbo, Jing Wang, Hamidou Cisse,Didier Doumtabe,Abdrahamane Traore, Hamadi Traore,
The New England journal of medicine (2024)
Zachary MacMillen, Kiara Hatzakis,Adrian Simpson,Melanie J. Shears,Felicia Watson,Jesse H. Erasmus,Amit P. Khandhar,Brandon Wilder,Sean C. Murphy,Steven G. Reed, James W. Davie, Marion Avril
npj Vaccinesno. 1 (2024): 1-15
Naveen Yadav, Chaitra Parthiban,Zachary P. Billman,Brad Stone,Felicia N. Watson,Kevin Zhou,Tayla Olsen,Irene Cruz Talavera,Annette M. Seilie, Anya C. Kalata, Jokichi Matsubara,Melanie J. Shears,
crossref(2023)
Yining Zhu, Jingyao Ma, Ruochen Shen,Jinghan Lin, Shuyi Li,Xiaoya Lu,Jessica L. Stelzel,Jiayuan Kong,Leonardo Cheng,Ivan Vuong,Zhi-Cheng Yao, Christine Wei,
Research Square (Research Square) (2023)
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