基本信息
浏览量:14
职业迁徙
个人简介
Dr. Ballinger’s group hypothesizes that mitochondrial – nuclear genetic interaction processes significantly influence common disease development. Because the genetic selection processes for mitochondrial – nuclear interaction are influenced by survival and reproductive success, the changing environmental challenges from original prehistoric conditions to contemporary (along with increased lifespan) have significantly affected cell function. In this regard, his work explores the influence of “mito-Mendelian” genetics upon bioenergetics, inflammation, metabolism, and nuclear gene expression. For these studies, he invented and has developed the Mitochondrial – Nuclear eXchange (MNX) model that enables unambiguous testing of mitochondrial and nuclear genetic backgrounds upon cell function and disease development. From this research, it is becoming clear that “mito-Mendelian” genetics influences cell function and response to acute and chronic stimuli. Consequently, the genetic basis for disease is not based solely upon Mendelian nor Mitochondrial genetics, but is the consequence of “mito-Mendelian” genetics. This concept is paradigm challenging. Current laboratory projects investigate the role for mito-Mendelian genetics upon various metabolic diseases (cancer, cardiovascular, ulcerative colitis and obesity).
AWARDS/HONORS:
Alexander Hollaender Distinguished Fellowship: U.S. Department of Energy
Environmental Pathology Fellowship: University of Vermont-NIH
Young Investigator Award: American Lung Association: New Hampshire-Vermont
Burroughs-Wellcome Nominee: University of Vermont
Outstanding Faculty Award, Molecular and Cellular Pathology Graduate Students
College of Science Academy of Distinguished Former Students Award, Texas A&M University
研究兴趣
论文共 87 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
bioRxiv : the preprint server for biology (2023)
引用0浏览0WOS引用
0
0
Journal of molecular and cellular cardiology (2023): 31-44
Molecular pain (2023): 17448069231195975
引用0浏览0WOS引用
0
0
Glycobiologyno. 8 (2023): 626-636
引用0浏览0WOS引用
0
0
Dominique C. Hinshaw,Ann Hanna, Tshering Lama-Sherpa,Brandon Metge,Sarah C. Kammerud,Gloria A. Benavides,Atul Kumar,Heba A. Alsheikh,Mateus Mota,Dongquan Chen,Scott Ballinger, Jeffrey C. Rathmell,
Cancer Researchno. 12_Supplement (2022): 2103-2103
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn