A strong focus of the lab is on circulating tumor-derived DNA (ctDNA) and its utility and applications as a cancer biomarker.
The lab also focuses on head and neck cancer genomics and translational research, stemming from Dr. Bratman’s clinical focus.
Methodologies frequently employed in the lab include in vitro and in vivo models of head and neck cancer, quantitative and digital PCR, next-generation sequencing technologies, and mining of publicly available genomics data.
The lab seeks to apply concepts of precision/personalized cancer medicine to the use of radiotherapy in curative treatment settings.