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职业迁徙
个人简介
For over 30 years, I have been fortunate enough to deliver key contributions towards our understanding of the organization and molecular composition of the innate immune response. My research activities comprise molecular biology, gene regulation, protein biosynthesis, structural biology, structure/function relations, measurements of functional activities, systems cross-talk, establishment of gene-targeted and transgenic mouse lines and their phenotypic characterisation in experimental models of disease. One of my key achievements over the recent years was my part in the discovery of a novel activation pathway of complement, now known as the lectin pathway. My work has led to the discovery of pathophysiological processes driven and maintained by dysregulation of this specific activation pathway linked to a plethora of chronic inflammatory human and animal diseases. This work was made possible through major funding support from both the MRC and the WELLCOME TRUST at programme grant level.
研究兴趣
论文共 220 篇作者统计合作学者相似作者
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Youssif M. Ali,George W. Carnell,Stefano Fumagalli,Domenico Mercurio, Serena Seminara,Nicholas J. Lynch,Priyanka Khatri, Chanuka H. Arachchilage,Luca Mascheroni,Clemens Kaminski,Charlotte L. George,Hazel Stewart,
Holt Charlotte Brinck, Halkjaer Lene, Dudler Tom,Schwaeble Wilhelm, Hansen Troels Krarup,Thiel Steffen, Ostergaard Jakob Appel
SCANDINAVIAN JOURNAL OF IMMUNOLOGYno. 4 (2024)
Frontiers in immunology (2023): 1192767-1192767
CLINICAL AND TRANSLATIONAL MEDICINEno. 7 (2022): n/a-n/a
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