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The S. Prakash laboratory concentrates on the study of DNA replication and DNA repair in yeast and in humans. The Prakash laboratory has made pioneering contributions to the understanding of DNA repair mechanisms that include nucleotide excision repair, base excision repair and mismatch repair. Their studies led to the discovery of translesion synthesis DNA polymerases and to the elucidation of their roles in replication of damaged DNA and they have contributed to the determination of the roles of DNA polymerase delta and DNA polymerase epsilon in replication.
The S. Prakash laboratory concentrates on the study of DNA replication and DNA repair in yeast and in humans. The Prakash laboratory has made pioneering contributions to the understanding of DNA repair mechanisms that include nucleotide excision repair, base excision repair and mismatch repair. Their studies led to the discovery of translesion synthesis DNA polymerases and to the elucidation of their roles in replication of damaged DNA and they have contributed to the determination of the roles of DNA polymerase delta and DNA polymerase epsilon in replication.
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Radhika Malik,Robert E Johnson, Iban Ubarretxena-Belandia, Louise Prakash,Satya Prakash, Aneel K Aggarwal
Nature structural & molecular biologypp.1-10, (2024)
Genes & developmentno. 5-6 (2024): 213-232
biorxiv(2023)
Journal of physics. Condensed matter : an Institute of Physics journalno. 28 (2023): 285801-285801
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