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个人简介
Dr. Aparicio’s research program encompasses the fields of cancer genomics, cancer evolution, single cell biology, mouse genetic models, high throughput screens, small molecule chemical probe development and translational breast cancer research. His work on the molecular taxonomy of breast cancer led to identification of new genes that could change the way breast cancer is diagnosed, and form the basis of next-generation treatments. This discovery was preceded by another breakthrough in decoding the genetic makeup of the most-deadly form of breast cancer, known as triple negative subtype (TNBC). Dr. Aparicio is also working to develop quantitative measures of clonal fitness in patients, including methods for single cell genome sequencing and PDX models of human cancer. He collaborates widely with other groups, with current projects including the genomic and biochemical analysis of lymphoma, ovarian cancer, and several rare pediatric cancers.
研究兴趣
论文共 327 篇作者统计合作学者相似作者
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Cold Spring Harbor perspectives in medicine (2024)
Marc J. Williams, Michael UJ Oliphant, Vinci Au, Cathy Liu, Caroline Baril, Ciara O'Flanagan,Daniel Lai,Sean Beatty, Michael Van Vliet, Jacky CH Liu, Lauren O'Connor, Walter L. Goh,
biorxiv(2024)
Elena Zaikova,Brian Y C Cheng, Viviana Cerda, Esther Kong,Daniel Lai,Amy Lum,Cherie Bates,Wendie den Brok,Takako Kono, Sylvie Bourque,Angela Chan, Xioalan Feng,
NPJ breast cancerno. 1 (2024): 3-3
Eric Lee, Dongkyu Lee, Wayne Fan,Andrew Lytle, Yuxiang Fu,David W. Scott,Christian Steidl,Samuel Aparicio,Andrew Roth
Cancer Researchno. 7_Supplement (2023): 5523-5523
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Research Square (Research Square) (2023)
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Farhia Kabeer, Goldman Lam, Naila Adam, Maxwell Douglas,Amal M. El-Naggar, Forouh Kalantari, Mengke Han, Vinci Au, Michael Van Vliet, Cindy Shen, Sean D. Beaty,Daniel T. H. Lai,
Cancer Researchno. 7_Supplement (2023): 2182-2182
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Eduardo A González-Solares, Ali Dariush,Carlos González-Fernández,Aybüke Küpcü Yoldaş, Alireza Molaeinezhad, Mohammad Al Sa'd,Leigh Smith,Tristan Whitmarsh, Neil Millar,Nicholas Chornay,Ilaria Falciatori,Atefeh Fatemi,
Biological imaging (2023): e11-e11
Si Tuen Lee-Hoeflich, Thinh Q. Pham, Don Dowbenko,Xander Munroe,James Lee,Li Li,Wei Zhou,Peter M. Haverty, Kanan Pujara,Jeremy Stinson,Sara M. Chan,Jeffrey Eastham-Anderson,
crossref(2023)
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