基本信息
浏览量:178
职业迁徙
个人简介
Søren Molin is Professor at Department of Systems Biology and Scientific Director at Novo Nordisk Centre for Biosustainabilty at the Technical University of Denmark. He received his PhD (1977) from Department of Microbiology at University of Copenhagen. He was employed as associate professor at the University of Southern Denmark 1977-83, during which he worked in the field of plasmid biology. In 1983 he became Professor at the Technical University of Denmark, where he established a research group focusing on biofilms. Since 2005 he has concentrated his research on microbial evolution in connection with chronic airway infections in humans. In 2010 he was a cofounder of Novo Nordisk Center for Biosustainability, where he directs a large research group working on design of bacterial cell factories.
The major research interest of the past 10 years has been microbial biofilms in relation to cell-cell interactions and developmental processes. The knowledge obtained in the course of this work is now being further developed in connection with detailed studies of microbial adaptation and evolution in cases of chronic infections. These current research activities are based on the assumption that fundamental studies of bacteria physiology and ecology are essential if we wish to understand and eventually interfere with such microbial infections. The investigations employ several methods providing global information about the cells’ genomes and functional genomics. In particular, specific clones of bacteria infecting airways of cystic fibrosis patients are studied. In connection with these studies evolution of antibiotic resistance is an important topic where the current focus point is resistance mechanisms involved in tolerance to anti-microbial peptides. Development of various types of laboratory model systems for simulation of human infections in vitro has been added to the research program.
Publications
Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis.
Marvig, Rasmus Lykke ; Madsen Sommer, Lea Mette ; Molin, Søren ; Johansen, Helle Krogh
in journal: Nature Genetics (ISSN: 1061-4036) (DOI: http://dx.doi.org/10.1038/ng.3148), vol: 47, pages: 57–64, 2015
Type: Journal article (Peer reviewed)
Status: Published | Year: 2015 | DOI: http://dx.doi.org/10.1038/ng.3148
Diversity of small RNAs expressed in Pseudomonas species
Gomez-Lozano, Mara ; Marvig, Rasmus Lykke ; Molina-Santiago, Carlos ; Tribelli, Paula Maria ; Ramos, Juan-Luis ; Molin, Søren
in journal: Environmental Microbiology Reports (ISSN: 1758-2229) (DOI: http://dx.doi.org/10.1111/1758-2229.12233), vol: 7, issue: 2, pages: 227-236, 2015
Type: Journal article (Peer reviewed)
Status: Published | Year: 2015 | DOI: http://dx.doi.org/10.1111/1758-2229.12233
Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients
Marvig, Rasmus Lykke ; Madsen Sommer, Lea Mette ; Jelsbak, Lars ; Molin, Søren ; Johansen, Helle Krogh
in journal: Future Microbiology (ISSN: 1746-0913) (DOI: http://dx.doi.org/10.2217/FMB.15.3), vol: 10, issue: 4, pages: 599-611, 2015
Type: Journal article (Peer reviewed)
Status: Published | Year: 2015 | DOI: http://dx.doi.org/10.2217/FMB.15.3
Electrochemical detection of pyocyanin as a biomarker for bacterial infections
Al Atraktchi, Fatima Al-Zahraa ; Svendsen, Winnie Edith ; Breum Andersen, Sandra ; Molin, Søren ; Johansen, Helle Krogh
Presented at: 25th European Society of Clinical Microbiology and Infectious Diseases, 2015, Copenhagen
Type: Poster
Status: Published | Year: 2015
研究兴趣
论文共 133 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Nature Communicationsno. 1 (2024): 1-12
Akbar Espaillat,Claudia Antonella Colque, Daniela Rago,Ruggero La Rosa,Søren Molin,Helle Krogh Johansen
bioRxiv (Cold Spring Harbor Laboratory) (2023)
引用0浏览0引用
0
0
bioRxiv (Cold Spring Harbor Laboratory) (2023)
引用0浏览0引用
0
0
bioRxiv (Cold Spring Harbor Laboratory) (2023)
引用0浏览0引用
0
0
Antonia Habich,Alibek Galeev, Veronica Chaves Vargas,Olga Vogler,Melanie Ghoul,Sandra Breum Andersen,Helle Krogh Johansen,Søren Molin,Ashleigh S. Griffin,Daniel Unterweger
bioRxiv (Cold Spring Harbor Laboratory) (2022)
引用0浏览0引用
0
0
MBIOno. 5 (2022)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn