Sidong Huang

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Research Interests
Functional Genomics to Guide Cancer Therapy
Our laboratory uses functional genomic tools to study cancer-relevant pathways and to guide cancer therapy. We aim to identify novel genes and networks that modulate response to cancer drugs, and to uncover genetic dependencies of cancer-relevant pathways that can be exploited therapeutically.

Research Interests

Papers共 99 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Discovery of RNA-Protein Molecular Clamps Using Proteome-Wide Stability Assays

Stanley I Goldstein, Alice C Fan, Zihao Wang, Sai K Naineni,Regina Cencic, Steve B Garcia-Gutierrez, Kesha Patel,Sidong Huang,Lauren E Brown,Andrew Emili, John A Porco

Journal of proteome researchno. 4 (2025): 2026-2039

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Curative Timed NK Cell-Based Immunochemotherapy Aborts Brain Tumour Recurrence Driven by Mesenchymal Glioma Stem Cells

Brian Meehan, Lata Adnani,Xianbing Zhu,Nadim Tawil, Delphine Garnier,Ichiro Nakano,Sidong Huang,Janusz Rak

Acta Neuropathologica Communicationsno. 1 (2025): 1-17

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ATR and PKMYT1 Inhibition Re-Sensitize a Subset of TNBC Patient-Derived Models to Carboplatin Inducing Mitotic Catastrophe

Juliet Guay,Hellen Kuasne,Catherine Chabot, Kathryn Bozek,Marguerite Buchanan,Yasamin Majedi,Adriana Aguilar-Mahecha,Eric Bareke,Tim Kong,Kangning Yang,Oluwadara Elebute, Ruining Guo,Anie Monast,Genevieve Morin,Sidong Huang,Morag Park,Mark Basik

biorxiv（2025）

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TSC2 Loss in Neural Progenitor Cells Suppresses Mrna Translation of Neurodevelopmental Genes

Pauline Martin,Krzysztof J Szkop,Francis Robert, Srirupa Bhattacharyya,Roberta L Beauchamp, Jacob Brenner, Nicholas E Redmond,Sidong Huang,Serkan Erdin,Ola Larsson,Vijaya Ramesh

Brain a journal of neurology (2025)

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SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-loops to Inhibit BRCA1-mediated Repair in Ovarian Cancer

Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu,Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue,Leora Witkowski, Elise Graulich,Jutta Steinberger, Selim Misirlioglu, Nicklas Bassani, Racim Sansal,Amber Yasmeen,Geneviève Morin, Jingjie Guo,Anie Monast, Virginie Pilon, Alica Valachová,Kitty Pavlakis,Lili Fu, Walter H Gotlieb,W Glenn McCluggage,David Huntsman, Alexander J R Bishop,Douglas A Levine,Morag Park,Yemin Wang,Brian Raught, William D Foulkes,Sidong Huang

Cancer research (2025)

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Mesenchymal Glioma Stem Cells Trigger Vasectasia—distinct Neovascularization Process Stimulated by Extracellular Vesicles Carrying EGFR

Cristiana Spinelli,Lata Adnani,Brian Meehan,Laura Montermini,Sidong Huang,Minjun Kim,Tamiko Nishimura,Sidney E. Croul,Ichiro Nakano,Yasser Riazalhosseini,Janusz Rak

Nature Communications（2024）

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TSC2 Loss in Neural Progenitor Cells Suppresses Translation of ASD/NDD-associated Transcripts in an Mtorc1- and MNK1/2-reversible Fashion

Pauline Martin,Krzysztof J Szkop,Francis Robert,Srirupa Bhattacharyya,Roberta L Beauchamp, Jacob Brenner, Nicholas E Redmond,Sidong Huang,Serkan Erdin,Ola Larsson,Vijaya Ramesh

bioRxiv the preprint server for biology (2024)

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Associate Professor

Papers共 99 篇Author StatisticsCo-AuthorSimilar Experts