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Besides her work on nucleic acid secondary structure prediction, Nussinov is also regarded as a pioneer in DNA sequence analysis for her work in the early 1980s. Nussinov’s algorithm for the prediction of RNA secondary structure is still the leading method. She proposed ‘Conformational Selection and Population Shift’ as an alternative to the textbook ‘Induced-Fit’ model in molecular recognition. Her recent studies unveiled the key role of allostery under normal conditions and in disease and the principles of allosteric drug discovery.
Dr. Nussinov serves as the Editor-in-Chief of PLOS Computational Biology and she is an elected Fellow of the Biophysical Society and the International Society for Computational Biology. She is a Highly Cited Researcher, earning them the mark of exceptional impact.
She also won an award from the AACR in 2017 for her paper on The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas.
Research Interests
Papers共 860 篇Author StatisticsCo-AuthorSimilar Experts
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JOURNAL OF PHYSICAL CHEMISTRY Bno. 21 (2024): 5175-5187
Science advancesno. 27 (2024): eadm9211-eadm9211
Trends in Pharmacological Sciencesno. 6 (2024): 503-519
biorxiv(2024)
Structure (2024)
Weiqiang Lu,Jiayan Cui,Wanyan Wang,Qian Hu,Yun Xue,Xi Liu, Ting Gong, Yiping Lu,Hui Ma,Xinyu Yang,Bo Feng,Qi Wang,
Nature communicationsno. 1 (2024): 4703-4703
PROTEIN SCIENCEno. 5 (2024)
JOURNAL OF CHEMICAL INFORMATION AND MODELINGno. 3 (2024): 862-873
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