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个人简介
Our research interests include investigations related to tumor biology, tumor dormancy, mechanism of action of angiogenesis inhibitors, self-assembly of polymeric architectures and novel approaches to target cancer. Throughout, we have maintained an interest in understanding the biological rationale for the design of polymer therapeutics suitable for transfer into clinical testing. Our primary interests are the molecular basis of tumor angiogenesis and the rational design of polymer therapeutics. Our research includes identification and characterization of genes and microRNAs associated with the switch from a dormant avascular tumor phenotype to a fast-growing angiogenic tumor in human cancers and their corresponding mouse models. We focus on the design and characterization of novel drug delivery platforms, including dendrimers and hyperbranched polymer–based nanoparticles, and the design of highly-selective targeting molecules integrating biology, chemistry, protein engineering, computational approaches, material sciences and nanotechnology to selectively guide drugs into pathological sites. Our vision is that novel approaches to target anticancer, anti-angiogenic drugs, miRNA and siRNAs to endothelial and tumor cells to potentially treat angiogenesis-dependent diseases could transform cancer into a chronically-manageable disease.
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论文共 240 篇作者统计合作学者相似作者
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Lior Orbach, Shelly Loewenstein, Veronika Lerman, Daniella Vaskovich,Ron Kleiner,Anat Globerson Levin,Ronit Satchi-Fainaro,Guy Lahat
ANNALS OF SURGICAL ONCOLOGYno. 1 (2024): S27-S28
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Lea Monteran,Nour Ershaid, Ye'ela Scharff,Yazeed Zoabi, Tamer Sanalla,Yunfeng Ding, Anna Pavlovsky,Yael Zait, Marva Langer,Tal Caller,Anat Eldar-Boock,Camila Avivi,
Cancer discovery (2024)
Eilam Yeini, Ronnie Frommer-Shapira, Alisa Talianski,Paula Ofek,Sabina Pozzi,Nitzan Albeck,Dikla Ben-Shushan,Galia Tiram,Sapir Golan,Ron Kleiner, Ron Sheinin,Shlomit Reich-Zeliger,
Cancer Researchno. 6_Supplement (2024): 4031-4031
Barbara Carreira,Rita C. Acúrcio,Ana I. Matos,Liane M. Moura, Ana C. Santos, Raquel Gouveia, Jéssica Cordeiro,Carina Peres, Daniela Vaskovich-Koubi,Ron Kleiner,Sabina Pozzi,Ronit Satchi-Fainaro,
Cancer Researchno. 6_Supplement (2024): 493-493
Ronit Satchi-Fainaro, Anne Krinsky, Anshika Katyal, Opal Avramoff,Eilam Yeini,Lena Neufeld, Sharon Halparin, Ronnie Frommer-Shapira
Cancer Researchno. 6_Supplement (2024): 651-651
Carina Peres,Ana I. Matos,Bárbara Carreira,Liane I. F. Moura,Ron Kleiner,Daniella Vaskovich‐Koubi, Keren Reshef,Shai Dulberg, Mafalda Verdial,João Conniot, Marta B. Afonso,Rita C. Acúrcio,
Advanced Functional Materials (2024)
Ronit Satchi-Fainaro, Opal Avramoff, Anshika Katyal,Eilam Yeini, Anne Krinsky,Yulia Liubomirski,Shai Dulberg,Galia Tiram, Ayelet Kaminitz, Jason Gill, Jessica Pedersen, Dana Bar-On,
Cancer Researchno. 6_Supplement (2024): 2361-2361
Cancer Researchno. 6_Supplement (2024): 5522-5522
Cancer Researchno. 6_Supplement (2024): 6749-6749
Daniella Vaskovich,Rita Acúrcio,Ron Kleiner,Barbara Carreira,Ana Matos,Helena Florindo,Ronit Satchi-Fainaro
Cancer Researchno. 6_Supplement (2024): 3208-3208
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