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Dr. Fan's research is focused on the development and deployment of single-cell and spatial multi-omics profiling technologies, often based on microfabricated devices, to investigate pathogenesis and therapeutic response of complex human diseases including cancer, autoimmunity, and cardiovascular disease. In particular, his laboratory is interested in hematologic malignancies, brain tumors, and systemic lupus erythematosus. He is also interested in cellular immune function characterization and the application to cancer immunotherapies. A microchip technology his laboratory developed for simultaneous measurement of 42 immune effector proteins in single cells, which remains the highest multiplexing to date for a single-cell protein secretion assay, has been commercialized as IsoCode and IsoLight, and currently used by tens of comprehensive cancer centers and pharmaceutical companies in the U.S. and around the world. Recently, his laboratory is working to develop high-spatial-resolution multi-omics sequencing technology, which may find wide-spread applications in developmental biology, cancer research, neuroscience, and immunobiology.
研究兴趣
论文共 242 篇作者统计合作学者相似作者
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CELL REPORTS MEDICINEno. 1 (2024)
Cell reports. Medicineno. 1 (2024): 101354-101354
Michalina Janiszewska, Doris P. Tabassum,Zafira Castano,Simona Cristea,Kimiyo N. Yamamoto,Natalie L. Kingston,Katherine C. Murphy,Shaokun Shu, Nicholas W. Harper, Carlos Gil Del Alcazar,Masa Aleckovic,Muhammad B. Ekram,
NATURE CELL BIOLOGY (2024)
Sebastian Birk, Irene Bonafonte-Pardàs, Adib Miraki Feriz, Adam Boxall,Eneritz Agirre, Fani Memi, Anna Maguza,Rong Fan,Gonçalo Castelo-Branco,Fabian J. Theis,Omer Ali Bayraktar,Carlos Talavera-López,
biorxiv(2024)
Zhiliang Bai,Dingyao Zhang,Yan Gao,Bo Tao, Shuozhen Bao,Archibald Enninful,Daiwei Zhang,Graham Su, Xiaolong Tian, Ningning Zhang,Yang Xiao,Yang Liu,
bioRxiv : the preprint server for biology (2024)
Michalina Janiszewska, Doris P Tabassum,Zafira Castaño,Simona Cristea,Kimiyo N Yamamoto,Natalie L Kingston,Katherine C Murphy,Shaokun Shu, Nicholas W Harper, Carlos Gil Del Alcazar,Maša Alečković,Muhammad B Ekram,
Nature cell biology (2024)
Yang Xiao,Graham Su,Yanxiang Deng, Tianyu Li,Sai Ma,Yang Liu,Gorazd B. Rosoklija, Madeline Mariani,Cheick Sissoko, Tingting Wu,Adrienne Santiago,Andrew J. Dwork,
NEUROPSYCHOPHARMACOLOGY (2023): 287-287
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Hiromitsu Asashima,Dongjoo Kim,Kaicheng Wang,Nikhil Lele,Nicholas C Buitrago-Pocasangre, Rachel Lutz,Isabella Cruz,Khadir Raddassi,William E Ruff,Michael K Racke, JoDell E Wilson, Tara S Givens,
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bioRxiv : the preprint server for biology (2023)
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