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His research is directed at the prevention oftype 2 diabetes and its complications especially cardiovascular disease, and on lipids and lipoproteins and their clinical importance . He is a Principal Investigator of the NIH funded Diabetes Prevention Program He has been principal Investigator of many studies funded either by industry or jointly with the NIH focused on the pharmacotherapy of diabetes and atherosclerotic disease prevention and management of type 2 diabetes. In addition he brings his expertise in these areas as an investigator to several collaborative NIH funded studies that include a study of stroke, a study of the effect of the built environment on development of the metabolic syndrome in recently arrived Cuban immigrants and an investigation of atherosclerosis risk in children with HIV on long-term antiretroviral therapy. He has a strong interest in undergraduate and postgraduate medical education, and was the Director of the Southeast Florida Diabetes Center Program, a State funded activity devoted mainly to education from 1996-2008. He is the ADA representative on the ACC/AHA committee developing the 2018 Guideline on the Management and Treatment of Cholesterol. He is active in mentoring Fellows in the Division of Endocrinology and medical residents in their research projects and in clinical lipidology and diabetology as Directorof the University of Miami Lipid Disorders Clinic and based on his experience and expertise as a diabetologist.
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