Rolph Pfundt frequently studies issues relating to Proband and Genetics. In his articles, he combines various disciplines, including Proband and Phenotype. He performs multidisciplinary studies into Phenotype and Haploinsufficiency in his work. He merges Haploinsufficiency with Mutation in his research. Rolph Pfundt conducts interdisciplinary study in the fields of Mutation and Hypotonia through his works. His Hypotonia study frequently links to related topics such as Genetics. He conducts interdisciplinary study in the fields of Gene and Intellectual disability through his works. Rolph Pfundt carries out multidisciplinary research, doing studies in Intellectual disability and Gene. His multidisciplinary approach integrates Copy-number variation and Gene duplication in his work.