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Research foci are cultivation-independent nucleic acids-based metagenomics and metatranscriptomics of complex microbial assemblages and recovery of novel genes and gene products from environmental samples such as soil, sediments, ice, and biofilms. The metagenomic screenings comprised function-based as well as sequence-based approaches. This work has led, i.e., to the successful identification and characterization proteases, cellulases, oxidoreductases, dehydratases, lipases, and DNA polymerases from metagenomes. To gain insights into the genomes of the uncultivated microorganisms and to determine metabolic potential and key functions of microbial communities in the studied environments direct sequencing and annotation of metagenomic DNA and cDNA (mRNA), and comparative genomics are carried out. Other lines of research include whole-genome sequencing, transcriptomics and functional genomics of archaea, bacteria, and microbial communities. The majority of the analyzed organisms is of industrial importance or pathogenic. The group also develops novel bioinformatic tools for data analysis and visualization.
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Microbiology spectrumno. 4 (2024): e0338023-e0338023
MICROBIOLOGY RESOURCE ANNOUNCEMENTSpp.e0001624-e0001624, (2024)
NUCLEIC ACIDS RESEARCHno. 3 (2024): 1404-1419
Giulia Ravagnan, Janne Lesemann, Moritz-Fabian Müller,Anja Poehlein,Rolf Daniel,Stephan Noack,Johannes Kabisch,Jochen Schmid
Frontiers in bioengineering and biotechnology (2024): 1378873-1378873
APPLIED AND ENVIRONMENTAL MICROBIOLOGYno. 3 (2024): e0127823-e0127823
Frontiers in microbiology (2024): 1374708-1374708
ISME JOURNALno. 1 (2024)
Microbiology Resource Announcements (2024)
Nature Sustainabilityno. 6 (2023): 683-695
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Dominik Schneider, Aygun Ganbarzade, Sina Post,Daniela Zühlke,Tjorven Hinzke,Jacqueline Hollensteiner,Anja Poehlein,Katharina Riedel,Rolf Daniel,Simon Roux
Microbiology resource announcementsno. 5 (2023): e00143-23-e0014323
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