Currently Dr. De Filippo is researching: The development of working renal units from stem cell sources in the laboratory for eventual transplantation in animal recipients as a viable donor kidney source, the use of amniotic fluid stem cells for cell therapeutic modes of therapy in acute and chronic renal failure, FDA-approved phase II clinical trial for tissue engineering of the bladder, isolation of progenitor cells for tissue engineering and cell therapy from amniotic fluid, multipotent stem cells and progenitor cells from amniotic fluid for the treatment of alport disease, the use of multipotent stem cells from amniotic fluid for fetal therapy for alport disease as a model for fetal therapies in genetic diseases of the kidney, the use of multipotent and progenitor stem cells from amniotic fluid for diabetes and diabetic nephropathy.