基本信息
浏览量:192
职业迁徙
个人简介
Area(s) of Expertise
Our laboratory focuses on the biology and genetics of CRISPR-Cas immune systems in bacteria. Using microbiology, molecular biology and genomics approaches, we investigate the use of CRISPR-Cas systems for three types of applications:
The exploitation of CRISPR spacer hypervariability for genotyping and phylogenetic studies of beneficial and pathogenic bacteria
Leveraging CRISPR-mediated interference for building up phage resistance in probiotic strains and starter cultures used in food manufacturing
Harnessing of Cas9-mediated, re-programmable dsDNA cleavage for genome editing in bacteria
These activities provide insights into the genetic and molecular processes that drive CRISPR-mediated adaptive immunity in bacteria and generate novel tools for the manipulation of industrially relevant organisms for food and biotechnological applications.
Our laboratory focuses on the biology and genetics of CRISPR-Cas immune systems in bacteria. Using microbiology, molecular biology and genomics approaches, we investigate the use of CRISPR-Cas systems for three types of applications:
The exploitation of CRISPR spacer hypervariability for genotyping and phylogenetic studies of beneficial and pathogenic bacteria
Leveraging CRISPR-mediated interference for building up phage resistance in probiotic strains and starter cultures used in food manufacturing
Harnessing of Cas9-mediated, re-programmable dsDNA cleavage for genome editing in bacteria
These activities provide insights into the genetic and molecular processes that drive CRISPR-mediated adaptive immunity in bacteria and generate novel tools for the manipulation of industrially relevant organisms for food and biotechnological applications.
研究兴趣
论文共 304 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
The CRISPR journalno. 2 (2024): 71-71
The CRISPR journalno. 1 (2024): 1-2
Foods (Basel, Switzerland)no. 13 (2023): 2455-2455
引用0浏览0WOS引用
0
0
Nature Reviews Bioengineeringno. 11 (2023): 799-816
引用0浏览0引用
0
0
Daniel B. Sulis,Xiao Jiang,Chenmin Yang, Barbara M. Marques,Megan L. Matthews,Zachary Miller, Kai Lan, Carlos Cofre-Vega,Baoguang Liu,Runkun Sun, Henry Sederoff,Ryan G. Bing,
Science (New York, N.Y.)no. 6654 (2023): 216-+
CRISPR JOURNALno. 5 (2023): 403-403
引用0浏览0WOS引用
0
0
CRISPR JOURNALno. 1 (2023): 1-1
Benjamin A. Adler,Marena Trinidad, Daniel Bellieny-Rabelo, Elaine Zhang, Hannah M. Karp,Petr Skopintsev,Brittney W. Thornton, Rachel F. Weissman,Peter H. Yoon,Linxing Chen,Tomas Hessler,Amy R. Eggers,
Nucleic acids research (2023)
引用0浏览0WOS引用
0
0
Nature Reviews Bioengineeringno. 11 (2023): 799-816
引用0浏览0WOSNATURE引用
0
0
CRISPR JOURNALno. 6 (2023): 493-501
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn