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个人简介
She completed her postdoctoral research in the Mammalian Genetics lab at the Cancer Research UK London Research Institute where she specialised in studying intestinal tissue stem cells and their function in homeostasis and cancer. As a Senior Scientist in the Adult Stem Cell lab at the Francis Crick Institute she turned her interests in mammalian cell differentiation to the study of cell fate decisions in adult pancreatic progenitors and began to explore their potential to treat diabetes.
Research interests
Our group is fascinated by the inherent plasticity of seemingly differentiated pancreatic cells and the molecular cues behind cell fate changes. Our work uncovered a latent capacity for regeneration in the pancreas, which could be harnessed to replace crucial insulin-producing cells lost to disease. The main goal in our lab is to decipher the fundamental regulatory networks involved in pancreatic cell fate decisions using adult pancreas organoids and induced pluripotent stem cells (iPSCs), and to apply this knowledge to new strategies in regenerative medicine for diabetes.
Research interests
Our group is fascinated by the inherent plasticity of seemingly differentiated pancreatic cells and the molecular cues behind cell fate changes. Our work uncovered a latent capacity for regeneration in the pancreas, which could be harnessed to replace crucial insulin-producing cells lost to disease. The main goal in our lab is to decipher the fundamental regulatory networks involved in pancreatic cell fate decisions using adult pancreas organoids and induced pluripotent stem cells (iPSCs), and to apply this knowledge to new strategies in regenerative medicine for diabetes.
研究兴趣
论文共 54 篇作者统计合作学者相似作者
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Frontiers in cell and developmental biology (2023): 1163825
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Rafael Jiménez-Izquierdo,Rosario Morrugares, Lucía Suanes-Cobos,Alejandro Correa-Sáez,Martín Garrido-Rodríguez, Laura Cerero-Tejero,Omar M. Khan,Susana de la Luna,Rocío Sancho,Marco A. Calzado
Teodora Manea,Jessica Kristine Nelson, Cristina Maria Garrone,Karin Hansson,Ian Evans,Axel Behrens,Rocio Sancho
Nature Communicationsno. 1 (2023): 1-17
CELL STEM CELLno. 4 (2023): 498-499
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Cell reportsno. 9 (2022): 110425-110425
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