This translational science laboratory aims to understand how cells of the innate immune system are involved in processes of tissue homeostasis, injury and repair.

Areas of particular interest focus around: (1) understanding the role of monocytes, macrophages and neutrophils in acute myocardial infarction; myocardial regeneration vs repair and in atherosclerosis and (2) how these cells are 'programmed' e.g. by extracellular vesicles and through by genetic / epigenetic and metabolic mechanisms.

He is co-PI of of the NovoNordisk Foundation supported Metabolite-related inflammation and disease (MeRIAD) consortium. He serves on the Editorial Board of the Journal of the American Journal of Cardiology (Section Editor, Clinical Cardiology).