Roberta Cavalli have a multi-year experience in the design and development of either conventional pharmaceutical formulations or innovative nanotechnology-based drug delivery systems, as well as their in vitro and in vivo characterization. Much research focused the attention on developing novel nanoparticulate formulations to improve the efficacy of the loaded therapeutic molecules. The incorporation of a therapeutic agent within a nanoformulation aims at changing the physico-chemical characteristics of the loaded molecule, modifying the pharmacokinetics and the biodistribution, magnifying the effectiveness and decreasing the side effects. RC developed various types of novel nanocarriers consisting of safe components, generally either polymers or lipids, admitted by the regulatory authorities to assure biocompatibility, biodegradability and low cytotoxicity.