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Dr. Gatenby spearheaded the formation of a new program at Moffitt titled Integrative Mathematical Oncology (IMO). The IMO brings to the Cancer Center a cadre of applied mathematicians to collaborate with tumor biologists and clinical oncologists. The goal is to use the mathematics developed for other nonlinear dynamical systems to examine the physiology of a tumor incorporating factors such as phenotypic evolution, intracellular communication pathways and interactions with microenvironmental factors including therapies. The program fosters continuous interaction between mathematicians and experimentalists as they form explicit comprehensive theoretical models to serve as a framework for understanding cancer’s development, progression and treatment. The IMO, led by Dr. Gatenby, represents an experiment in rethinking paradigms in medical research. A key purpose of the IMO is to provide the quantitative methods that will allow experimentalists and clinicians to frame their hypotheses, simulate their experimental design in-silico, and identify first principles that govern cancer growth and treatment. Dr. Gatenby aims to make progress using methods that have been successful in the physical sciences for centuries —through an iterative partnership between mathematically-oriented theoreticians, biologists and clinical physicians.
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论文共 435 篇作者统计合作学者相似作者
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iScienceno. 4 (2024): 109614-109614
Sareh Seyedi, Ruthanne Teo,Luke Foster, Daniel Saha,Lida Mina,Donald Northfelt,Karen S. Anderson,Darryl Shibata,Robert Gatenby,Luis H. Cisneros,Brigid Troan,Alexander R. A. Anderson,
CANCERSno. 2 (2024)
Crystal Griffith, Dominique Abrahams, Antonio Ortiz, Alexandra Tassielli,Joseph Johnson,Robert Gatenby,Smitha Pillai
Cancer Researchno. 6_Supplement (2024): 375-375
Asmaa El-Kenawi,William Dominguez-Viqueira, Min Liu,Shivanshu Awasthi,Julieta Abraham-Miranda, Aysenur Keske,KayLee K. Steiner,Leenil Noel,Amparo N. Serna, Jasreman Dhillon,Robert J. Gillies, Xiaoqing Yu,
crossref(2023)
Journal of clinical oncology : official journal of the American Society of Clinical Oncologyno. 28 (2023): 4469-+
openalex(2023)
Jill A. Gallaher,Pedro M. Enriquez-Navas,Kimberly A. Luddy,Robert A. Gatenby, Alexander R.A. Anderson
crossref(2023)
Asmaa El-Kenawi,William Dominguez-Viqueira, Min Liu,Shivanshu Awasthi,Julieta Abraham-Miranda, Aysenur Keske,KayLee K. Steiner,Leenil Noel,Amparo N. Serna, Jasreman Dhillon,Robert J. Gillies, Xiaoqing Yu,
crossref(2023)
Asmaa El-Kenawi,William Dominguez-Viqueira, Min Liu,Shivanshu Awasthi,Julieta Abraham-Miranda, Aysenur Keske,KayLee K. Steiner,Leenil Noel,Amparo N. Serna, Jasreman Dhillon,Robert J. Gillies, Xiaoqing Yu,
crossref(2023)
Sareh Seyedi, Ruthanne Teo,Luke Foster, Daniel Saha,Lida Mina,Donald Northfelt,Karen S Anderson,Darryl Shibata,Robert Gatenby,Luis Cisneros,Brigid Troan,Alexander R A Anderson,
bioRxiv : the preprint server for biology (2023)
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