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Professor Robert (Bob) Brown is Chair in Translational Oncology in the Department of Surgery and Cancer within the Faculty of Medicine at Imperial College. His post is a joint appointment between Imperial College London and Institute of Cancer Research where he is Professor of Translational Oncology in the Section of Medicine.
Professor Brown’s work focuses on epigenetics, patient stratification and drug resistance research, with a particular focus on ovarian cancer. He facilitates development of compounds which can reverse epigenetic silencing and is using molecular biomarker assays to aid the preclinical development and clinical use of these compounds. Recent research interests include the effect of DNA damaging agents on the epigenome, epigenetic targeting using CRISPR and whether systems oncology approaches can be used to monitor and stratify patients for targeted treatments.
Professor Brown’s work focuses on epigenetics, patient stratification and drug resistance research, with a particular focus on ovarian cancer. He facilitates development of compounds which can reverse epigenetic silencing and is using molecular biomarker assays to aid the preclinical development and clinical use of these compounds. Recent research interests include the effect of DNA damaging agents on the epigenome, epigenetic targeting using CRISPR and whether systems oncology approaches can be used to monitor and stratify patients for targeted treatments.
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论文共 306 篇作者统计合作学者相似作者
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Stroke Geneticspp.251-281, (2024)
Sarah Laing,Björn Kruspig,Robin Shaw,Leah Officer,Sarah C. Edwards, Danielle McKinven,Ya‐Ching Hsieh,Ian Powley,Nicola Brady, Ross A. Pennie, Rwp Kwan,Anthony Lima,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Aydan Kahriman,James Bouley,Idil Tuncali, Elif O Dogan,Mariana Pereira,Thuyvan Luu,Daryl A Bosco, Samer Jaber,Owen M Peters,Robert H Brown,Nils Henninger
Brain : a journal of neurologyno. 12 (2023): 5139-5152
Cancer immunology researchno. 4 (2023): 332-340
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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BJOG : an international journal of obstetrics and gynaecologyno. 10 (2022)
BJOG: An International Journal of Obstetrics & Gynaecology (2022)
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