R.L. Mackman - AI Profile | 人才画像

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Papers共 143 篇Author StatisticsCo-AuthorSimilar Experts

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Oral Dosing of the Nucleoside Analog Obeldesivir is Efficacious Against RSV Infection in African Green Monkeys

Jared Pitts, J. Lizbeth Reyes Zamora,Savrina Manhas,Thomas Aeschbacher, Josolyn Chan, Vincent Cutillas, Varsha Nair, Nicolas C. Riola,Arya Vijjapurapu,Meghan S. Vermillion,Stacey Eng,Christopher Richards,Dong Han,Jason K. Perry,Subhra Chaudhuri, Iris Liu,Clarissa Martinez,Nadine Peinovich,Kai-Hui Sun, Arthur Cai,Ross Martin,Jasmine Moshiri,Charlotte Hedskog,Darius Babusis,Dustin S. Siegel,Rao Kalla,Vasanthi Avadhanula,Pedro A. Piedra,Kim Stobbelaar,Peter L. Delputte,Caleb Marceau,Roberto Mateo,Jenny Svarovskaia,Hongmei Mo,Raju Subramanian,Richard L. Mackman,Tomas Cihlar,Simon P. Fletcher,John P. Bilello

biorxiv（2025）

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Antiviral Target Compound Profile for Pandemic Preparedness

James F Demarest,Ruxandra Draghia-Akli,Tomas Cihlar, Kenneth Bradley,John A T Young, Richa Chandra, Sujata Vaidyanathan, Margaret Chu-Moyer, Christopher L Lynch, Andrew Campbell, Kumar Singh Saikatendu,John P Bilello, Yoshihiko Murata,Marnix van Loock,Aeron C Hurt, Timothy Tellinghuisen, Lee Ruggiero,Richard Mackman, Nina M Hill, John C Pottage, INTREPID Alliance

Nature reviews Drug discoveryno. 2 (2025): 151-152

Cited0Views0WOSNATUREBibtex

Pharmacokinetics and Metabolism of Broad-Spectrum Antivirals Remdesivir and Obeldesivir with a Consideration to Metabolite GS-441524: Same, Similar, or Different

Darius Babusis,Cynthia Kim, Jesse Yang, Xiaofeng Zhao, Guoju Geng, Carmen Ip, Nathan Kozon, Hoa Le, Jennifer Leung,Jared Pitts,Dustin S. Siegel,Rao Kalla, Bernard Murray,John P. Bilello, Roy Bannister,Richard L. Mackman,Raju Subramanian

Virusesno. 6 (2025): 836

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Discovery of GS-7682, a Novel 4′-Cyano-modified C-Nucleoside Prodrug with Broad Activity Against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys

Dustin S. Siegel,Hon C. Hui,Jared Pitts,Meghan S. Vermillion, Kazuya Ishida,Davin Rautiola, Michael Keeney,Hammad Irshad,Lijun Zhang,Kwon Chun,Gregory Chin, Bindu Goyal,Edward Doerffler,Hai Yang,Michael O. Clarke, Chris Palmiotti,Arya Vijjapurapu,Nicholas C. Riola,Kirsten Stray,Eisuke Murakami,Bin Ma,Ting Wang,Xiaofeng Zhao,Yili Xu,Gary Lee,Bruno Marchand,Minji Seung, Arabinda Nayak,Adrian Tomkinson, Nani Kadrichu,Scott Ellis,Ona Barauskas,Joy Y. Feng,Jason K. Perry,Michel Perron,John P. Bilello,Philip J. Kuehl,Raju Subramanian,Tomas Cihlar,Richard L. Mackman

Journal of Medicinal Chemistryno. 15 (2024): 12945-12968

Cited1Views0WOSBibtex

Discovery and Synthesis of GS-7682, a Novel Prodrug of a 4′-Cn-4-aza-7,9-dideazaadenosine C-Nucleoside with Broad-Spectrum Potency Against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys

biorxiv（2024）

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Therapeutic Treatment with an Oral Prodrug of the Remdesivir Parental Nucleoside is Protective Against SARS-CoV-2 Pathogenesis in Mice

Carolina Digital Repository (University of North Carolina at Chapel Hill) (2022)

Cited57Views0WOSSCIENCEBibtex

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