Richard E Lee
Departments of Infectious Diseases (C.S.
M.W.F., C.O.R., S.J.), Chemical Biology and Therapeutics (R.T., R.E.L.), Structural Biology (M.-K.Y., S.W.W.), and St. Jude Graduate School of Biomedical Sciences (S.W.W.), St. Jude Children's Research Hospital, Memphis, Tennessee
关注
立即认领
分享
关注
立即认领
分享
基本信息
浏览量:0
职业迁徙
个人简介
Richard E. Lee obtained his honours degree and Ph.D. in chemistry from the University of Newcastle-Upon-Tyne, UK. Postdoctoral fellowships followed in the laboratories of Patrick Brennan at Colorado State University, Fort Collins, USA, studying mycobacterial cell wall pathways as drug targets, and George Fleet at the University of Oxford, UK, studying the design and synthesis of inhibitors of bacterial carbohydrate-modifying enzymes. He then moved to a research fellow position in the laboratory of Clifton E. Barry III in the intramural programme of the US National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA, where his studies focused on the development of new anti- Mycobacterium tuberculosis compounds. These studies led to the discovery of SQ109, which subsequently advanced to clinical trials for tuberculosis. He then accepted a faculty position in the Department of Pharmaceutical Sciences at the University of Tennessee Health Science Center, where he established a productive programme focused on anti-bacterial medicinal chemistry. Recently, he moved his laboratory to St Jude Children's Research Hospital, where he continues his studies on the discovery and development of novel chemotherapeutic agents to treat catastrophic diseases, with a focus on problematic bacterial infections. He has published over 80 papers and patents in this area.
研究兴趣
论文共 247 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Chitra Subramanian,Matthew W Frank, Rajaa Sukhun, Christopher E Henry,Anna Wade, Mallory E Harden,Satish Rao,Rajendra Tangallapally,Mi-Kyung Yun,Stephen W White,Richard E Lee,Uma Sinha,
The Journal of pharmacology and experimental therapeuticsno. 1 (2024): 171-180
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAno. 2 (2024): e2314101120-e2314101120
Antimicrobial agents and chemotherapyno. 3 (2024): e0139923-e0139923
bioRxiv (Cold Spring Harbor Laboratory) (2023)
JOURNAL OF ANTIBIOTICSno. 1 (2023): 1-2
Caroline R. Buchholz, Molly S. Sneddon, Joseph E. Mcpherson,Sourav Das,Clifford T. Gee,Michael J. Grillo,Sergio C. Chai,Richard E. Lee,Taosheng Chen,Daniel A. Harki,Anang A. Shelat,William C. K. Pomerantz
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn