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Professor Cannon is a molecular microbiologist interested in how microorganisms cause oral diseases and in how treatments for patients with these diseases can be improved. His research has a number of themes, one being oral adhesion. He is interested in how oral microbes, particularly yeast, adhere and colonize surfaces in the oral cavity.
He has found that saliva increases the adhesion of the yeast Candida albicans to several oral surfaces, including denture acrylics and voice prosthesis silicone. He is interested in the formation of oral biofilms, how microorganisms communicate within biofilms, and ways of inhibiting pathogenic biofilm formation.
C. albicans is a polymorphic fungus that grows mainly as yeast or mycelia. Professor Cannon is using metabolomics to investigate the changes in metabolism that are associated with the change from yeast to hyphal growth. A major focus of his research is the drug resistance of human fungal pathogens. He has found that clinically significant fungal drug resistance is due to energy-dependent drug efflux from the cell. His research group has developed a unique system for expressing and studying these efflux pumps in baker's yeast Saccharomyces cerevisiae.
He has found that saliva increases the adhesion of the yeast Candida albicans to several oral surfaces, including denture acrylics and voice prosthesis silicone. He is interested in the formation of oral biofilms, how microorganisms communicate within biofilms, and ways of inhibiting pathogenic biofilm formation.
C. albicans is a polymorphic fungus that grows mainly as yeast or mycelia. Professor Cannon is using metabolomics to investigate the changes in metabolism that are associated with the change from yeast to hyphal growth. A major focus of his research is the drug resistance of human fungal pathogens. He has found that clinically significant fungal drug resistance is due to energy-dependent drug efflux from the cell. His research group has developed a unique system for expressing and studying these efflux pumps in baker's yeast Saccharomyces cerevisiae.
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L. T. Friedlander, W. D. A. Wallace,J. M. Broadbent, S. M. Hanlin, K. M. Lyons,R. D. Cannon,P. R. Cooper
AUSTRALIAN DENTAL JOURNALno. 1 (2024): 29-39
Genesno. 2 (2023): 272-272
Advanced Healthcare Materialsno. 25 (2023)
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SSRN Electronic Journal (2023)
ADVANCED HEALTHCARE MATERIALSno. 25 (2023)
Gerodontology (2023)
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Biomaterials (2023): 122356-122356
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