With his group, he is particularly interested in the chemistry of wine stability and aging, including research on barrier properties of closures, and in the development and applications of targeted and non-targeted analytical tools to understand the mechanisms at the origin of the long-lasting stability of great wines. In close collaboration with the Analytical BioGeoChemistry research unit of Prof. Dr. Philippe Schmitt-Kopplin at Helmholtz Center and Technical University Munich, he has introduced and developed the concept of oenolomics, based on the consideration of wine as whole complex biological system constantly evolving under environmental conditions, which requires integrated methodologies such as ultra-high-resolution MS for the development of non-targeted comprehensive analyses. R. Gougeon is author or co-author of +110 international peer-reviewed publications, and coordinator of the Wine Active Compounds (WAC) international conference series https://ubwac.com/.