基本信息
浏览量:291
职业迁徙
个人简介
Dr. Regina Santella's research involves the use of biomarkers for the detection of human exposure to environmental and occupational carcinogens in molecular epidemiology studies to identify causative factors, susceptible populations, and preventive interventions. Her work has allowed the determination of exposure to carcinogens by the measurement of their binding to DNA with highly specific and sensitive immunoassays using monoclonal and polyclonal antibodies that her laboratory has developed. These studies have demonstrated higher levels of DNA damage in those with environmental or occupational exposures and in subjects with breast, lung, and liver cancer compared to controls. The role of genetic susceptibility in cancer risk is also being investigated with an emphasis on DNA repair capacity. Current studies seek to understand the role of environmental/lifestyle factors on epigenetic changes in DNA methylation and microRNA expression, how they impact cancer risk as well as whether epigenetic changes can be used for early diagnosis of cancer.
研究兴趣
论文共 664 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Hepatology (Baltimore, Md.) (2024)
Sasinya N. Scott, Marvin Siguencia,Frank Z. Stanczyk,Michaela F. Hartmann,Stefan A. Wudy, Melissa White,Wendy K. Chung,Regina M. Santella,Mary Beth Terry,Lauren C. Houghton
JOURNAL OF THE ENDOCRINE SOCIETYno. 3 (2024): bvad161-bvad161
Monique Slowly, Arce Domingo-Relloso,Regina M. Santella, Karin Haack, Daniele M. Fallin, Mary Beth Terry,Dorothy A. Rhoades,Miguel Herreros-Martinez, Esther Garcia-Esquinas,Shelley A. Cole, Maria Tellez-Plaza,Ana Navas-Acien,
Cancer Causes & Controlno. 4 (2024): 661-669
Research square (2023)
引用0浏览0WOS引用
0
0
crossref(2023)
Cancer Researchno. 5_Supplement (2023): P4-03
引用0浏览0引用
0
0
Hiroshi Mitsumoto,Ken Cheung,Björn Oskarsson,Howard F. Andrews, Grace E. Jang,Jinsy A. Andrews,Jaimin S. Shah, Joseph Americo Fernandes,Martin McElhiney,Regina M. Santella
Trialsno. 1 (2023): 449-17
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn